School of Bio-Medical Sciences (Bio-Medical) Collections
Recent Submissions
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Histological Demonstration of the Organisms Causing Human Tungiasis in Eastern Uganda
(Journal of Cytology & Histology, 2020)Background: Tungiasis, a neglected tropical ecto-parasitic disease, has resurged in Sub-Saharan Africa, causing public concern and at times confusing diagnosis. In October 2010, following widespread human disease within ... -
Investigation of a haemorrhagic febrile illness in Nakaseke District, Central Uganda: A case series report
(African Journal of Parasitology Research, 2020-02-05)Persons in Nakaseke and neighbouring districts within Central Uganda suffered from a haemorrhagic febrile illness. Four tested positive for the Crimean-Congo Haemorrhagic Fever (CCHF) virus, five for the Rift Valley Fever ... -
Prevalence of staphylococcus aureus isolated from the lower genital tract of mothers in labour possessing selected virulence factor genes in Uganda.
(Makerere University, 2019-11-28)Background: Staphylococcus aureus is one of the gram positive bacteria colonizing the human body. It colonizes in approximately one third of the general population worldwide. It particularly colonizes the skin, nasal ... -
Human herpes virus 8 DNA in blood as a marker of Kaposi’s Sarcoma in HIV positive Ugandan patients.
(makerere university, 2020-01-28)Introduction; Kaposi’s Sarcoma (KS) is an abnormal excessive growth of blood vessels associated with human herpes virus 8 (HHV-8), as the causative agent. In HIV infected individuals, HHV-8 is the major cause of AIDS-related ... -
Prevalence and Incidence of Carriage of Carbapenem Resistant Enterobacteriaceae among Patients Admitted to Mulago Hospital General Intensive Care Unit
(Makerere university, 2019-09-01)Background: Carbapenem Resistant Enterobacteriaceae CRE) are among the major causes of nosocomial infections contributing to increase morbidity and mortality in the ICU. Carbapenem being the last choice of beta lactams for ... -
Evaluation of the effect of pim6 on the induction of hiv-1 expression from memory cd4+ t cells of virally suppressed hiv-1 patients attending TASO clinic, Mulago.
(Nakimuli Cynthia, 2020-01-07)Background: Latent HIV-1 reservoirs harbour human immunodeficiency virus type 1 (HIV-1) proviral DNA which can be reactivated to express viral RNA. Memory CD4+ T cells in HIV-infected persons are critical as HIV reservoirs, ... -
Monocyte activation and dysregulation in treated and untreated hiv-1 infected Ugandans.
(Makerere University, 2018-08-30)Introduction: Mechanism for increased non-AIDs co morbidities in HIV-1infected individuals on combinatorial antiretroviral therapy (cART) still requires exploration. This is majorly attributed to chronic monocyte activation ... -
Characterization of extended spectrum βlactamases elaborated in enterobacteriaceae in Uganda.
(Makerere University, 2017-08-23)Background: Extended spectrum β-lactamase producing Enterobacteriaceae (ESBL-PE) have been identified as a major cause of both community and facility associated infections and are closely linked to faecal carriage in the ... -
Perceptions, Knowledge and factors that Influence the Acceptability of Genetically Modified Foods in Kampala City
(Makerere university, 2019-08)Introduction: Food is one of the most important basic needs for the survival of all human beings. With the rapid growing population in the world, the molecular genetics has become a very important tool in the improvement ... -
Comparison of Ackers culture to Inpouch culture for the diagnosis of Trichomonas vaginalis among Symptomatic Females at Mulago Hospital
(Makerere university, 2015-10)Background: Trichomoniasis is the most curable sexually transmitted Infection (STI) in the world, caused by the genital Trichomonas vaginalis infection. The Trichomona vaginalis is a single celled flagellated eukaryote ... -
The challenge posed by lay catechists’ poverty to their effectiveness in evangelization in the light of redemptoris missio in Kasanga Parish, Kasese Catholic Diocese
(Makerere University, 2015-04)It is true the Bishop is primarily the agent of Evangelization; this becomes very vivid when he has a very good team of coworkers, like the priests, Nuns, religious brothers and Catechists. Right back from the early ... -
A molecular phylogenetic and modeling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoriaa, Uganda
(Makerere University, 2019-11-29)Fishing communities (FCs) in Uganda have a greater HIV burden relative to other high-risk groups and the general population (GP). As a result of the very high HIV-1 incidence rates, they have been hypothesized to act ... -
Molecular Characterization of Uropathogenic Escherichia coli Isolates from Clients with Community-acquired Urinary Tract Infections Attending Outpatient Clinics in Kampala District
(Makerere University, 2019-08)Background: Community-acquired urinary tract infection (CA-UTI) commonly caused by uropathogenic Escherichia coli (UPEC) is mainly treated empirically but there is increased resistance to different common antimicrobial ... -
Phenotypic Diagnosis and Characterization of Fungaemia using Conventional Blood Culture
(Makerere university, 2019-08-01)Background: Fungaemia is highly associated with immunocompromised populations as a results of long hospital stays, intensive care unit admissions and oncology. Blood culture is the most reliable conventional method in the ... -
Effect of N-Acetyl cysteine on Moringa oleifera aqueous leaf extract-induced hepatotoxicity in Wistar Albino rats
(2019-12)Background: Moringa oleifera (M. oleifera) is a highly valued medicinal plant widely used to treat various ailments. It has a variety of nutritional and medicinal properties that are attributed to the various phytochemical ... -
VARIATIONS IN TRIM5α AND CYCLOPHILIN A GENES AMONG HIV-1 ELITE CONTROLLERS AND NON CONTROLLERS IN UGANDA
(Makerere University, 2019-12-10)Background: Human immunodeficiency virus type-1 (HIV-1) elite controllers represent a unique population that controls viral replication in the absence of antiretroviral therapy (ART). Various genetic, immunologic and ... -
E valuation of the Impact of HIV-1 Infections on Cytomegalovirus Specific T cells Responses
(Makerere University, 2019-10-30)Background: Incomplete understanding of the effect of HIV-1 infection on T cell immune response to HCMV is a barrier to development of better control strategies for HCMV infection in HIV-1 infected individuals. Depletion ... -
Compensatory mutations in rpoA, rpoC and rpoD genes among rifampicin-resistant Mycobacterium tuberculosis isolates from Uganda
(Makerere University, 2019-11-11)Background; Mycobacterium tuberculosis can acquire resistance to rifampicin through mutations in the rpoB gene. This is normally accompanied by the fitness cost which however can be mitigated by the acquired secondary ... -
Association of Carbapenemase Genes with Phenotypic Resistance to Carbapenems among Gram Negative Bacteria
(Winnie Binoga, 2019-12-05)BACKGROUND: Carbapenem drugs are the last resort antibacterial agents used in the treatment of Extended Spectrum Beta-Lactamase multi drug resistant Gram negative bacterial infections. Resistance to these drugs is reported ... -
INNATE IMMUNE SYSTEM RECOVERY AFTER LONG TERM ANTIRETROVIRAL THERAPY IN AN AFRICAN COHORT
(Makerere University, 2019-08-30)Background: Restoration of the immune system has been observed in many cohorts worldwide upon initiation of antiretroviral therapy. However, we have reported partial restoration of the T cell subset function despite seven ...
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