School of Bio-Medical Sciences (Bio-Medical) Collections
Recent Submissions
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Carbapenem resistance among gram negative rods isolated from surgical site infections at Mulago and Kawempe National referral hospitals
(Makerere University, 2024-01-04)Background: Surgical site infections are becoming increasingly difficult to manage with the rise of drug resistance among causative bacteria. Contributing to this, the use of foreign implants in certain surgeries pauses ... -
Prevalence of Nasal Carriage of Methicillin Resistant Staphylococcus Aureus Among Patients, Health Care Workers and Patients’ Care Takers at Kabale Regional Referral Hospital, South Western Uganda
(Archives of Clinical and Medical Microbiology, 2023-10-24)Background Methicillin Resistant Staphylococcus aureus (MRSA) is a type of Gram-positive bacterium that is genetically different from other strains of Staphylococcus aureus by virtue its capability to overcome the actions ... -
Antimicrobial Resistance Patterns and Molecular Characterization of Klebsiella pneumoniae in Clinical Isolates at Mbarara Regional Referral Hospital
(Scientific Research Publishing, 2019)Background: Klebsiella pneumoniae is one of the most frequent opportunistic pathogens causing a range of infections and being resistant for beta-lactamases (ESBL) and Carbapenemases. Aim: The aim of the present study was ... -
Bacteriological profle, antibiotic susceptibility and factors associated with neonatal Septicaemia at Kilembe mines hospital, Kasese District Western Uganda
(BMC, 2021)Introduction: Neonatal septicaemia is one of the most common leading causes of neonatal morbidity and mortality in developing countries. It is estimated to afect more than 30 million people worldwide annually, potentially ... -
Assessment of biosafety and biorisk management practices among medical laboratory students in two institutions in Uganda
(Elsevier, 2022)Medical laboratory workers handle clinical specimens, which are a threat of exposure to infectious agents. Notably, medical laboratory science students report for internships with only theoretical knowledge of biosafety ... -
Status of pulmonary fungal pathogens among individuals with clinical features of pulmonary tuberculosis at Mbarara University Teaching Hospital in Southwestern Uganda
(Therapeutic advances in infectious disease, 2021)Background: Pulmonary mycoses are important diseases of the respiratory tract caused by pulmonary fungal pathogens. These pathogens are responsible for significant morbidity and mortality rates worldwide; however, less ... -
Investigating Metabolic and Molecular Ecological Evolution of Opportunistic Pulmonary Fungal Coinfections: Protocol for a Laboratory-Based Cross-Sectional Study
(JMIR, 2023-12)Background: Fungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms and microbiome ... -
Plasmodium falciparum genetic diversity and multiplicity of infection based on msp‑1, msp‑2, glurp and microsatellite genetic markers in Sub-Saharan Africa: a systematic review and meta-analysis
(BMC, 2024)Background In sub-Saharan Africa (SSA), Plasmodium falciparum causes most of the malaria cases. Despite its crucial roles in disease severity and drug resistance, comprehensive data on Plasmodium falciparum genetic ... -
A comparison of frequencies and function of myeloid derived suppressor cells (MDSCS) IN TB/HIV co-infected and HIV mono-infected individuals in Uganda
(Makerere University, 2023)Background Myeloid-derived suppressor cells (MDSC) encompass a subset of myeloid cells, which suppress both innate and adaptive immune functions. These cells negatively regulate the immune function either by arginine ... -
Sero-antigen prevalence of lymphatic filariasis and risk factors of podoconiosis in Busiriba Sub-county, Kamwenge District, Southwestern Uganda, August–September 2018
(BMC, 2024)Objective Given the neglected nature of filariasis, especially in Uganda where data are scarce, this cross-sectional study aimed to determine the sero-antigen prevalence of lymphatic filariasis and risk factors associated ... -
Incidence and etiology of catheter associated urinary tract infection among admitted patients at Kabale Regional Referral Hospital, South Western Uganda
(Scientific Research Publishing, 2019)Introduction: Catheter Associated Urinary Tract Infection is the most common hospital acquired infection worldwide. Urinary Tract Infections among catheterised patients are on rise regardless of antibiotic use and this is ... -
Clindamycin resistance among methicillin resistant staphylococcus aureus isolated from human and respective household swine in greater Kabale Region—South Western Uganda
(Scientific Research Publishing, 2019)Introduction: S. aureus is recognized as the common cause of nosocomial and community-acquired infections. Macrolide-Lincosamide-Streptogramin B (MLSB) is thought to be alternative therapies against MRSA infections. Clindamycin ... -
Functioning and control of phagocytosis
(IntechOpen, 2023)Phagocytosis is a very complex and versatile process that contributes to immunity through a series of events that is it’s sometimes referred to the Come and Eat me process. Due to the recognition ingestion and digestion ... -
Laboratory Diagnosis of Candidiasis
(IntechOpen, 2022-08)The burden of Candidiasis continues to increase and so does the Candida species. Although Candida species are closely similar phenotypically, they differ from each other in terms of epidemiology, genetic characteristics, ... -
Diversity and distribution of Spa Types among Methicillin resistant staphylococcus aureus isolated from humans and livestock in Kabale District - South Western Uganda
(Journal of Veterinary Health Science, 2022)Background: S. aureus is a skin and mucosal bacterial commensal of both humans and animals which has evolved as an important pathogen implicated to cause various infections. High levels of antibiotic use have resulted into ... -
Detection of clinically relevant respiratory viruses and their temporal dynamics in sputum of tuberculosis patients on anti-TB drugs at Naguru Hospital, Kampala, Uganda
(Makerere University, 2024)Background Tuberculosis is one of the leading infectious causes of death in the world, with nearly 10 million new cases diagnosed each year, resulting into an estimated 1.3 million deaths(1). The relationship between M. ... -
Antimicrobial stewardship practices and quality of antibacterial use in children under five and women in labour with obstetric risk factors in selected health facilities in Uganda
(Makerere University, 2024)Introduction Bacterial infections are a leading cause of morbidity and mortality in Ugandan hospitalised children under the age of five. Disparities exist in using antibacterial agents to treat bacterial infections at ... -
Detection of mycobacterium tuberculosis complex DNA in CD34 positive versus CD34-Negative peripheral blood mononuclear cells and the determinants of IGRA positivity in latent Tuberculosis
(Makerere University, 2023)Background Tuberculin skin test (TST) and interferon gamma release assay (IGRA), currently used to diagnose latent tuberculosis infection (LTBI) have low positive predictive values for progression to active tuberculosis ... -
A machine learning approach to predict E. coli antibacterial resistance using whole-genome sequencing data
(Makerere University, 2023)Background: Antimicrobial resistance (AMR) is a significant global health threat, particularly impacting low- and middle-income countries(LMICS) such as Uganda, where reliable and rapid methods for detecting AMR in E. coli ... -
Transcriptome analysis of micro-RNAs associated with COVID-19 disease
(Makerere University, 2023-11)The host microRNA (miRNA), which is essential for maintaining the epithelial cell barrier in the respiratory tract as well as controlling viral entry and reproduction, plays a significant role in COVID-19 infection. ...