Search
Now showing items 1-10 of 20
Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
(Elsevier, 2012-01-01)
Background Hormonal contraceptives are used widely but their eff ects on HIV-1 risk are unclear. We aimed to assess
the association between hormonal contraceptive use and risk of HIV-1 acquisition by women and HIV-1 ...
NeuroAIDS in Africa
(Informa Healthcare, 2010)
In July 2009, the Center for Mental Health Research on AIDS at the National
Institute of Mental Health organized and supported the meeting “NeuroAIDS
in Africa.” This meeting was held in Cape Town, South Africa, and ...
Community-acquired pneumonia in Ugandan adults: short-term parenteral ampicillin therapy for bacterial pneumonia
(The American Society of Tropical Medicine and Hygiene, 2001)
A hospital-based prospective study of 99 patients with community-acquired pneumonia (CAP) was carried out in Kampala, Uganda. We evaluated microbiological etiologies, clinical features and effectiveness of short term ...
HIV/AIDS patients display lower relative bioavailability of Efavirenz than healthy subjects
(Adis Data Information BV., 2011)
Background: Pharmacokinetic studies of antiretroviral drugs are often conducted in adult healthy subjects, and the results are extrapolated to HIV/AIDS patients. HIV/AIDS, however, is known to cause morphological and ...
Bacteraemia among severely malnourished children infected and uninfected with the human immunodeficiency virus-1 in Kampala, Uganda
(BioMed Central, 2006-11-07)
Background: To establish the magnitude of bacteraemia in severely malnourished children, and describe the types of bacteria and antimicrobial sensitivity by HIV status. Method: Isolates were recovered from 76 blood specimens. ...
Quantitative assessment of the sensitivity of various commercial reverse transcriptases based on armored HIV RNA
(Public Library of Science, 2010)
Background: The in-vitro reverse transcription of RNA to its complementary DNA, catalyzed by the enzyme reverse transcriptase, is
the most fundamental step in the quantitative RNA detection in genomic studies. As such, ...
Monocyte activation and dysregulation in treated and untreated hiv-1 infected Ugandans.
(Makerere University, 2018-08-30)
Introduction: Mechanism for increased non-AIDs co morbidities in HIV-1infected individuals on combinatorial antiretroviral therapy (cART) still requires exploration. This is majorly attributed to chronic monocyte activation ...
Simulation of clonal expansion and latent HIV reservoir size prediction using machine learning in virally suppressed individuals in Uganda
(Makerere University, 2022-07)
Background: HIV can survive as pro-viruses that do not undergo transcription mostly within resting memory CD4+ T cells despite prolonged antiretroviral therapy (ART). This Latent Viral Reservoir (LVR) has an extremely long ...
Role of vaginal microbiome in host susceptibility to HIV infection among pregnant Ugandan women: inflammatory response and epithelial barrier integrity
(Makerere University, 2021-10)
Background: Pregnant women are a key target population in the prevention of new HIV infections, and their protection can be extrapolated to their unborn children during pregnancy and at birth. The role of vaginal microbiota ...
Assessment of microbiological quality of herbal preparations used in the treatment of malaria, cough and HIV in Kampala district
(Makerere University, 2022-02)
In Uganda, herbal medicine is widely used in the treatment and prevention of various conditions including cough, malaria and HIV opportunistic infections. The demand for herbal products has increased among many consumers ...