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Bacteraemia among severely malnourished children infected and uninfected with the human immunodeficiency virus-1 in Kampala, Uganda
(BioMed Central, 2006-11-07)
Background: To establish the magnitude of bacteraemia in severely malnourished children, and describe the types of bacteria and antimicrobial sensitivity by HIV status. Method: Isolates were recovered from 76 blood specimens. ...
Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
(Elsevier, 2012-01-01)
Background Hormonal contraceptives are used widely but their eff ects on HIV-1 risk are unclear. We aimed to assess
the association between hormonal contraceptive use and risk of HIV-1 acquisition by women and HIV-1 ...
Community-acquired pneumonia in Ugandan adults: short-term parenteral ampicillin therapy for bacterial pneumonia
(The American Society of Tropical Medicine and Hygiene, 2001)
A hospital-based prospective study of 99 patients with community-acquired pneumonia (CAP) was carried out in Kampala, Uganda. We evaluated microbiological etiologies, clinical features and effectiveness of short term ...
HIV/AIDS patients display lower relative bioavailability of Efavirenz than healthy subjects
(Adis Data Information BV., 2011)
Background: Pharmacokinetic studies of antiretroviral drugs are often conducted in adult healthy subjects, and the results are extrapolated to HIV/AIDS patients. HIV/AIDS, however, is known to cause morphological and ...
NeuroAIDS in Africa
(Informa Healthcare, 2010)
In July 2009, the Center for Mental Health Research on AIDS at the National
Institute of Mental Health organized and supported the meeting “NeuroAIDS
in Africa.” This meeting was held in Cape Town, South Africa, and ...
CDd4 t- cell immune responses in haart-treated hiv-infected adults who attain normal CD4 counts in a Ugandan cohort
(Makerere University, 2014-05)
Background: Majority of HIV-infected individuals who start HAART at CD4 counts <200 cells/µl show a marked CD4+T-cell increase to absolute CD4 counts above 500 cells/µl. The CD4+ T-cell count is the main measure for immune ...
Evaluation of the impact of HIV-1 infections on Cytomegalovirus Specific T cells responses
(Makerere University, 2019-10-30)
Background: Incomplete understanding of the effect of HIV-1 infection on T cell immune response to HCMV is a barrier to development of better control strategies for HCMV infection in HIV-1 infected individuals. Depletion ...
PREVALENCE OF VIROLOGICAL SUPPRESSION AND PATTERNS OF ACQUIRED HIV DRUG RESISTANCE AMONG INDIVIDUALS ON FIRST-LINE ANTIRETROVIRAL THERAPY IN FISHERFOLK COMMUNITIES IN UGANDA
(2018-10-03)
Background: The UNAIDS targets sustained viral suppression among at least 90% of HIV individuals on antiretroviral therapy (ART), yet viral load (VL) monitoring is rarely done in resource-limited settings due to high costs. ...
Long term non-progressor-derived CD4+ T Cell In-Vitro susceptibility to HIV-1 infection
(Makerere University, 2018-09-01)
Introduction: World over, there are antiretroviral therapy naïve individuals infected with HIV who maintain their CD4+T cell count above 500 cells/μl over 7-10 years (termed as Long Term Non-progressors, LTNP). A subset ...
Quantitative assessment of the sensitivity of various commercial reverse transcriptases based on armored HIV RNA
(Public Library of Science, 2010)
Background: The in-vitro reverse transcription of RNA to its complementary DNA, catalyzed by the enzyme reverse transcriptase, is
the most fundamental step in the quantitative RNA detection in genomic studies. As such, ...