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In vitro efficacy of bacteriophages against Extended-spectrum β-Lactamase producing Escherichia coli Isolated from Patients with Urinary Tract Infections
(Makerere University, 2021-04)Background: Escherichia coli, a gram-negative bacterial pathogen, which harbors extended spectrum β-lactamase enzymes (ESBLs) is the major cause of UTIs. The wide spread emergence and expansion of ESBL producing E. coli ... -
Knowledge and Practices of Malaria Prevention and Control among Caretakers of Children Less Than 5 Years in Kiryandongo Refugee Settlement Camp.
(Makerere University, 2023-11-26)Introduction: Malaria remains the most common disease and the leading cause of admission at 56% and death (24%) in the refugee camps. Uganda currently hosts over 1.4 million refugees and Kiryandongo refugee camp is one of ... -
Prevalence and factors associated with depression among young adults living with HIV attending the Infectious Diseases Institute
(Makerere University, 2023-09-20)Introduction: Depression among young adults living with HIV increases their risk of complications from HIV and has been consistently associated with disruption of the important developmental process, subsequently leading ... -
Evaluation of antidepressant effects and safety of Lavendula angustifolia aqueous and total crude leaf extracts in Wistar albino rats.
(Makerere University, 2023-07-28)Introduction: Depression continues to be a major problem in Ugandan population and communities’ use medicinal plants like L. angustifolia (Lavandula angustifolia) for its treatment.Objective: To establish the antidepressant ... -
The political economy of adolescent mental health in Uganda: a case study among actors and adolescents in Kampala District.
(Makerere University, 2023)Background: More than half of Uganda’s population is below 16 years of age. These children and adolescents have particularly been exposed to increased risk of mental health conditions due to extreme poverty and a history ... -
Multidrug resistant Escherichia coli on chicken farms in Arua District, West Nile, Uganda: prevalence, antimicrobial resistance patterns, and public health risks
(Makerere University, 2023-11)Background: Antimicrobial resistance in food-animals threatens public health and food security. Much as chicken farms harbour resistant E. coli, its epidemiology in Uganda is still not well understood. This study determined ... -
Evaluation of the Diagnostic Validity of the HIV VISITECT CD4 Point-of-Care Rapid Diagnostic Test Using PIMA Analyzer as the Gold Standard in Uganda.
(Makerere University, 2023-09-30)Background: HIV remains prevalent in Uganda, and the cluster of differentiation-4 (CD4) markers are widely used to support and monitor disease progression. Objectives: This study aimed to compare the diagnostic validity ... -
Prevalence of undernutrition and its associated factors among children with sickle cell disease aged 6-59 months at Mulago National Referral Hospital Kampala, Uganda.
(Makerere University, 2023-11)Introduction: Sickle cell disease (SCD) significantly contributes to under-five morbidity and mortality in sub-Saharan Africa and increases vulnerability to undernutrition. However, limited studies exist on the prevalence ... -
Mutations in MDR-TB Isolates from Bedaquiline-Resistance Conferring Mulago Hospital Kampala, Uganda
(Makerere University, 2023-11-20)Introduction: In 2018, based on an evidence-based policy, the World Health Organization (WHO) updated its guidelines on the treatment of drug-resistant tuberculosis with recommendation of bedaquiline as a core drug in the ... -
Acceptability of TeleMental Health and its influencing factors among adolescent patients, caretakers, and mental health professionals at Butabika Hospital
(Makerere University, 2023-11)Background: Mental disorders are a significant cause of disability worldwide, Uganda inclusive. In 2019, they accounted for 4.92% and 3.94% of the disease burden in the world and Uganda, respectively. Adolescents are at a ... -
Uptake of COVID-19 Vaccination and Associated Factors among Persons Living with Diabetes Mellitus at Kiruddu Referral Hospital in Kampala, Uganda
(Makerere University, 2023-11)Background: Diabetes mellitus (DM) is associated with severe coronavirus disease (COVID-19) outcomes, including death, and full COVID-19 vaccination is the mainstay for preventing infection and severe disease among high-risk ... -
Prevalence of herbal medicine use and its association with renal dysfunction among patients on Tenofovir Antiretroviral Treatment based regimen at ISS Clinic Mulago
(Makerere University, 2023-11-16)Introduction HIV/AIDS is a major public health issue globally, with about 1.4 million infected people in Uganda by 2020. The prevalence of herbal medicine (HM) use among people living with human immunodeficiency virus ... -
Prevalence and perceptions of physical activity and healthy diet for the prevention and control of hypertension among HIV-positive clients at the Infectious Diseases Institute in Kampala, Uganda.
(Makerere University, 2023-11-17)Introduction: There is a rising burden of hypertension among PLHIV in Uganda, with the estimated prevalence in HIV care settings ranging from 15% to 32.3%. To address this challenge, the Ministry of Health has incorporated ... -
L everaging on the Cross-Reactivity and recovery of leptospira serovars in stored cultures to mitigate limitations of the Microscopic Agglutination Test
(Makerere University, 2023-11-13)Leptospirosis is one of the most widely spread bacterial zoonotic that is endemic in subtropical and tropical countries; accounting for a global annual incidence of 1.03 million human cases and 58,900 deaths. (Alinaitwe ... -
Estimating HIV prevalence and associated factors among Multidrug resistant tuberculosis patients in treatment centres in Uganda for the period 2017-2019; A comparison of methods
(Makerere University, 2023-11-27)Background: Multidrug resistant tuberculosis (MDR-TB) is a major clinical challenge, particularly in patients with human immunodeficiency virus (HIV) co-infection. The main objective of this study was to determine the ... -
Prevalence of uncontrolled hypertension and associated factors among adult HIV-infected patients on integrated HIV and hypertension care at Mulago National Referral Hospital, Uganda.
(Makerere University, 2023-11-24)Background: The integration of hypertension (HTN) management into HIV care is the most sustainable approach to addressing the burden of uncontrolled HTN among people living with HIV (PLHIV). However, HTN control is still ... -
Genomic determinants of virulence and antimicrobial resistance in colistin resistant Klebsiella pneumoniae isolates from Mulago National Referral Hospital
(Makerere University, 2023-08-29)Introduction: Multidrug resistance and high virulence in K. pneumoniae are of particular concern and have emerged as critically alarming threats to the global community. Worringly, K.pneumoniae has become resistant to ... -
Evaluation of the ameliorative effects of the methanolic and total crude extracts of Persea americana seeds on biochemical and haematological parameters in wistar albino rats induced with type 2 diabetes mellitus.
(Makerere University, 2023-11)Diabetes Mellitus is a chronic hyperglycaemic condition caused by low insulin production with 2 major types i.e., Type 1 and Type 2 DM (NIDDM). Type 2 DM accounts for 90% of DM cases and its global prevalence is expected ... -
Assessing the influence of monitoring practices on data use in decision-making at public health organizations; A case study of Zamzam Foundation, Somalia.
(Makerere University, 2023-11)Introduction: Monitoring and evaluation is at the center of sound governance arrangements globally, regionally, nationally and locally as well. It is necessary for the achievement of evidence-based decision-making, budget ... -
Prevalence and Correlates of Obesity among Private Day Primary School Going Children (9-12 years) in Kampala City - Central Uganda
(Makerere University, 2022-05)Introduction: Childhood obesity is one of the greatest public health challenges of our time and whereas it affects all children, it greatly affects primary school going children. More than one third of children are affected ...
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