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Descriptive study on prevalence of bacteremia and the profiles of antimicrobial resistance among febrile patients admitted to the medical emergency ward of Mulago Hospital, Uganda
(Makerere University, 2015-04)
Introduction: Bacteremia is associated with significant morbidity and mortality in the developing world. In Uganda, antibiotic susceptibility testing is not routinely done among patients suspected to have sepsis. This ...
Molecular epidemiology of antimicrobial resistance at a human-animal interface in pastoralist community of Kasese District, Uganda
(Makerere University, 2021-04)
Background: Intensive usage of antimicrobials in the management of animal diseases may cause selection for resistance among microorganisms. Transmission of resistant bacteria from the wild and domestic food animals to ...
Comparative genomics and antibiotic – resistance determinants of clinical pseudomonas aeruginosa isolates from Kenya
(Makerere University, 2022)
Pseudomonas aeruginosa is a leading cause of nosocomial infections worldwide. It causes a range of debilitating infections, have a propensity for developing antimicrobial resistance, and present with a variety of dangerous ...
Colistin resistance among gram negative rods carried in the intestinal tract of patients admitted in the ICU of Mulago National Referral Hospital
(Makerere University, 2022-04)
Background: The limited options for treatment of infections caused by MDR or XDR bacteria prompted the reintroduction of colistin, which coupled with extensive use in food-producing animals is driving increasing resistance ...
Molecular Characterization of Uropathogenic Escherichia coli Isolates from Clients with Community-acquired Urinary Tract Infections Attending Outpatient Clinics in Kampala District
(Makerere University, 2019-08)
Background: Community-acquired urinary tract infection (CA-UTI) commonly caused by uropathogenic Escherichia coli (UPEC) is mainly treated empirically but there is increased resistance to different common antimicrobial ...
Molecular epidemiology and antimicrobial resistance determinants of Neisseria gonorrhoeae among males with urethritis in Kampala, Uganda
(Makerere University, 2023-09-21)
Gonorrhoea is a highly prevalent bacterial sexually transmitted infection (STI) that negatively impacts sexual and reproductive health (SRH) and that is also greatly associated with serious clinical sequelae. Gonorrhoea ...
Employing whole genome sequencing to elucidate the pathogenic and Antimicrobial resistance potential of Klebsiella Oxytoca clinical isolates from Mulago Referral National Hospital in Uganda
(Makerere University, 2023-11-13)
Introduction: Klebsiella oxytoca (K. oxytoca) comprises a complex of related Gram negative opportunistic bacterial pathogens with scantly explored emerging antimicrobial resistance globally. Evidence shows shared virulence ...