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HIV/AIDS patients display lower relative bioavailability of Efavirenz than healthy subjects
(Adis Data Information BV., 2011)
Background: Pharmacokinetic studies of antiretroviral drugs are often conducted in adult healthy subjects, and the results are extrapolated to HIV/AIDS patients. HIV/AIDS, however, is known to cause morphological and ...
Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)
Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one
of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as
it jeopardizes the efforts to ...
Correlation of plasma HIV-1 p24 antigen levels with viral load in samples of HIV positive patients on ART in Uganda
(Makerere University, 2022-12)
Globally, a total of 38.0 million people living with HIV, of which 1.7 million people became newly infected with HIV in 2019. Additionally, an average of 690,000 people died from AIDS-related illnesses in 2019, and 26 ...