School of Bio-Medical Sciences (Bio-Medical): Recent submissions
Now showing items 221-240 of 423
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Longitudinal changes in cd4+ and cd8+t cell phenotype and activation marker expression among cryptococcal meningitis patients initiating on anti retroviral therapy
(Makerere University, 2017-12-04)Introduction: Since the introduction of antiretroviral therapy (ART), the prognosis for HIV-1 patients has improved immensely with CD4+T cell recovery and viral suppression. Early initiation of ART has been associated with ... -
Interferon Sensitivity Profiles of HIV-1 Transmitter Founder Viruses of Subtypes A, D and AD Recombinants in Uganda.
(Makerere University, 2021-02-08)ABSTRACT Background: In 80–90% of HIV-1 discordant partners, infection of the naive partner always results from the successful transmission and propagation of a single virus variant, termed the Transmitter Founder (TF) ... -
Antibody responses to Mycobacterial glycans and glycolipids as potential correlates of protection from mycobacterium tuberculosis infection in BCG vaccinated children
(Makerere University, 2021-04-01)Background: Globally, tuberculosis (TB) has remained the main cause of death from a single infectious pathogen. The only licensed TB vaccine to date, BCG, has variable efficacy. We need to understand the mechanism ... -
Barriers to partner HIV serostatus disclosure among postnatal mothers on option b+ in Rukungiri district
(Makerere University, 2019-12-02)Introduction; Self-disclosure of one’s positive HIV serostatus to partners is an important step in the pathway of transmission prevention through sexual risk reduction and uptake of treatment and support services. Disclosure ... -
Pulmonary dimorphic fungal infections in HIV infected patients with NON-TB chronic cough at Mulago Hospital, Uganda
(Makerere University, 2021-03)Introduction: Dimorphic fungi cause infection following inhalation of spores (conidia) into the pulmonary system. In the lower respiratory tract the conidia transform into the yeast phase which are engulfed by alveolar ... -
Prognostic factors for overall survival of patients with prostate cancer in Kyadondo county, Uganda
(Makerere University, 2021-02-24)Background: Prostate cancer (PCa) remains the most common cancer among men in sub-Saharan Africa (SSA). Uganda has the highest incidence and mortality of PCa in the East Africa region. The overall survival of patients with ... -
Prevalence of Helicobacter pylori infection during pregnancy and influence on the pregnancy anemia intervention package in Uganda among mothers at Kawempe Health Centre
(Makerere University, 2020-03)The National Anemia Policy (2002) specifies an intervention package for anemia in pregnancy which consists of iron and folic acid supplementation, and malaria and hook worm control. However, the prevalence of anemia in ... -
Histological Demonstration of the Organisms Causing Human Tungiasis in Eastern Uganda
(Journal of Cytology & Histology, 2020)Background: Tungiasis, a neglected tropical ecto-parasitic disease, has resurged in Sub-Saharan Africa, causing public concern and at times confusing diagnosis. In October 2010, following widespread human disease within ... -
Investigation of a haemorrhagic febrile illness in Nakaseke District, Central Uganda: A case series report
(African Journal of Parasitology Research, 2020-02-05)Persons in Nakaseke and neighbouring districts within Central Uganda suffered from a haemorrhagic febrile illness. Four tested positive for the Crimean-Congo Haemorrhagic Fever (CCHF) virus, five for the Rift Valley Fever ... -
Prevalence of staphylococcus aureus isolated from the lower genital tract of mothers in labour possessing selected virulence factor genes in Uganda.
(Makerere University, 2019-11-28)Background: Staphylococcus aureus is one of the gram positive bacteria colonizing the human body. It colonizes in approximately one third of the general population worldwide. It particularly colonizes the skin, nasal ... -
Human herpes virus 8 DNA in blood as a marker of Kaposi’s Sarcoma in HIV positive Ugandan patients.
(makerere university, 2020-01-28)Introduction; Kaposi’s Sarcoma (KS) is an abnormal excessive growth of blood vessels associated with human herpes virus 8 (HHV-8), as the causative agent. In HIV infected individuals, HHV-8 is the major cause of AIDS-related ... -
Prevalence and Incidence of Carriage of Carbapenem Resistant Enterobacteriaceae among Patients Admitted to Mulago Hospital General Intensive Care Unit
(Makerere university, 2019-09-01)Background: Carbapenem Resistant Enterobacteriaceae CRE) are among the major causes of nosocomial infections contributing to increase morbidity and mortality in the ICU. Carbapenem being the last choice of beta lactams for ... -
Evaluation of the effect of pim6 on the induction of hiv-1 expression from memory cd4+ t cells of virally suppressed hiv-1 patients attending TASO clinic, Mulago.
(Nakimuli Cynthia, 2020-01-07)Background: Latent HIV-1 reservoirs harbour human immunodeficiency virus type 1 (HIV-1) proviral DNA which can be reactivated to express viral RNA. Memory CD4+ T cells in HIV-infected persons are critical as HIV reservoirs, ... -
Monocyte activation and dysregulation in treated and untreated hiv-1 infected Ugandans.
(Makerere University, 2018-08-30)Introduction: Mechanism for increased non-AIDs co morbidities in HIV-1infected individuals on combinatorial antiretroviral therapy (cART) still requires exploration. This is majorly attributed to chronic monocyte activation ... -
Characterization of extended spectrum βlactamases elaborated in enterobacteriaceae in Uganda.
(Makerere University, 2017-08-23)Background: Extended spectrum β-lactamase producing Enterobacteriaceae (ESBL-PE) have been identified as a major cause of both community and facility associated infections and are closely linked to faecal carriage in the ... -
Perceptions, Knowledge and factors that Influence the Acceptability of Genetically Modified Foods in Kampala City
(Makerere university, 2019-08)Introduction: Food is one of the most important basic needs for the survival of all human beings. With the rapid growing population in the world, the molecular genetics has become a very important tool in the improvement ... -
Comparison of Ackers culture to Inpouch culture for the diagnosis of Trichomonas vaginalis among Symptomatic Females at Mulago Hospital
(Makerere university, 2015-10)Background: Trichomoniasis is the most curable sexually transmitted Infection (STI) in the world, caused by the genital Trichomonas vaginalis infection. The Trichomona vaginalis is a single celled flagellated eukaryote ... -
The challenge posed by lay catechists’ poverty to their effectiveness in evangelization in the light of redemptoris missio in Kasanga Parish, Kasese Catholic Diocese
(Makerere University, 2015-04)It is true the Bishop is primarily the agent of Evangelization; this becomes very vivid when he has a very good team of coworkers, like the priests, Nuns, religious brothers and Catechists. Right back from the early ... -
A molecular phylogenetic and modeling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoriaa, Uganda
(Makerere University, 2019-11-29)Fishing communities (FCs) in Uganda have a greater HIV burden relative to other high-risk groups and the general population (GP). As a result of the very high HIV-1 incidence rates, they have been hypothesized to act ... -
Molecular Characterization of Uropathogenic Escherichia coli Isolates from Clients with Community-acquired Urinary Tract Infections Attending Outpatient Clinics in Kampala District
(Makerere University, 2019-08)Background: Community-acquired urinary tract infection (CA-UTI) commonly caused by uropathogenic Escherichia coli (UPEC) is mainly treated empirically but there is increased resistance to different common antimicrobial ...