School of Bio-Medical Sciences (Bio-Medical): Recent submissions
Now showing items 181-200 of 423
-
Evaluation of the efficacy and safety of combining Carica Papaya Linn, Vernonia Amygdalina Delile, Artemisinin and Iodine as potential agents in the management of Breast Cancer
(Makerere University, 2021-12-25)Background: Carica papaya Linn (CP), Vernonia amygdalina Delile (VA), dihydroartemisinin (DHA) and molecular iodine (I2) were reported to have antiproliferative and cytotoxic activities on breast cancer but their anticancer ... -
Whole exome sequencing uncovers genetic predisposition to pediatric HIV disease progression and hyperhemolysis syndrome
(Makerere University, 2022-07)Background: Populations of African ancestry hold a disproportionate burden of infectious and non-infectious diseases. Genetic variants, with population allele frequencies ranging from rare to common variants, are believed ... -
Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as it jeopardizes the efforts to ... -
Assessment of microbiological quality of herbal preparations used in the treatment of malaria, cough and HIV in Kampala district
(Makerere University, 2022-02)In Uganda, herbal medicine is widely used in the treatment and prevention of various conditions including cough, malaria and HIV opportunistic infections. The demand for herbal products has increased among many consumers ... -
Social networks in gross anatomy dissection room and students' performance at Makerere University College of Health Sciences
(Makerere University, 2019-09-23)Introduction: Social interactions between students in the gross anatomy dissection room are a major and underexplored part of undergraduate education. Yet understanding how learning relationships form inside the dissection ... -
Healthcare workers’ experiences and processes undertaken in decision making for life-sustaining treatment in the intensive care units of Mulago National Referral, and Nakasero Hospitals
(Makerere University, 2022-04-28)Introduction: This study explored the experiences and processes undertaken by healthcare providers with regards to decision making for administering Life-Sustaining Treatment (LST) in Uganda. The specific objectives were: ... -
Attitudes and practices of herbalists towards the informed consent process
(Makerere University, 2022)Introduction: Informed Consent (IC) is a major cornerstone in medical ethics that is expected to be implemented universally in healthcare. The growing use of herbal medicines in developing countries has aroused concerns, ... -
Knowledge, attitudes and practice of ethics among plant agricultural researchers at the National Agricultural Research Laboratories, Kawanda-Uganda
(Makerere University, 2022-04-25)Background: Plant agricultural research plays an important role and contributes significantly to human health and livelihood. With the current advancements in technology, this research is not exempt from ethical issues and ... -
Internship Situation Analysis Survey Report
(College of Health Sciences, Makerere University, 2022-05)Internship is a mandatory pre-registration training required for licensure of doctors in Uganda. During the internship, medical workers acquire practical skills, attitudes and knowledge critical for them to work without ... -
Genotypic and phenotypic characterization of HIV-1 transmitted/founder viruses and their effect on cytokine profiles and disease progression among acutely infected Ugandans
(Makerere University, 2022)Virus-host interaction early after transmission elicit changes that are known to impact the course of the infection and clinical outcome. The nature of the virus that initiates the infection seems to play a key role. For ... -
Evaluation of contractile activity of the extracts of Gynandropsis gynandra Linn on isolated rabbit uterus and ileum
(Makerere University, 2022)Diarrhea due to exaggerated GIT motility and maternal death due to delayed labor remain serious health challenges; and among the leading causes of mortality globally especially among children and pregnant mothers respectively. ... -
Prevalence and histological types of kidney disease in autopsied persons at Kampala Capital City Authority Mortuary.
(Makerere University, 2022-02)Introduction: It is estimated globally that in 2016, 5-10 million people died from kidney dis-ease (KD) and about 1.7 million died from acute kidney injury. In sub Saharan Africa the prevalence of KD is quite high and is ... -
Expression of ARID1A in Penile Squamous Cell Carcinoma and its association with age, histological subtypes and grades in the Pathology Department, Makerere University.
(Makerere University, 2022-03)Background: About ninety-five percent (95%) of penile carcer arise in the squamous epithelium, giving rise to squamous cell carcinoma. Worldwide, the incidence and global health burden of penile cancer is in the range of ... -
Vegf protein expression in gastric cancer and associated clinical pathological features as seen at the Department of Pathology, Makerere University
(Makerere University, 2022-03-17)Background: Gastric cancer is the 5th most common cancer accounting for 5.7% of all cancers in the world and causes about 783,000 deaths annually. In Uganda the incidence of gastric cancer increased from 0.8 cases per ... -
BCL-2 protein expression in oral squamous cell carcinoma and associated clinicopathological features as seen at the Pathology Department, Makerere University
(Makerere University, 2021-11)Background: Predicting clinical behavior of oral squamous cell carcinoma based on histopathological analysis requires immunohistochemical supplementation with biomarkers like Bcl-2 protein that can be used in prognostic ... -
The evaluation of effect of canarium schweinfurthii leaf and pulp extracts on blood glucose levels in oral glucose load - induced hyperglycemia, heamatological parameters and safety in wistar albino rats
(Makerere University, 2022-03-14)Background: Canarium schweinfurthii (C. schweinfurthii) is a common medicinal plant in Uganda used as food and as medicine in the management of Diabetes mellitus type 2 and anemia by local communities and traditional ... -
Role of vaginal microbiome in host susceptibility to HIV infection among pregnant Ugandan women: inflammatory response and epithelial barrier integrity
(Makerere University, 2021-10)Background: Pregnant women are a key target population in the prevention of new HIV infections, and their protection can be extrapolated to their unborn children during pregnancy and at birth. The role of vaginal microbiota ... -
Participants’ understanding of informed consent for genomic research: a case of the CAfGEN study.
(Makerere University, 2020-07)Introduction: For informed consent to be valid, prospective participants are required to have adequate understanding of research prior to making decisions about participation. Studies have reported that participants in ... -
Magnitude of bilateral cataracts and factors associated with delayed uptake of cataract surgery among adult patients with operable cataract seen at Mulago Hospital.
(Makerere University, 2022-01-20)Background. Cataract is an opacity in the natural lens of the eye that causes visual impairment to vision of less than 6/9. Cataract causes 51% of global blindness and any delay in timely uptake of cataract surgery results ... -
Renal function of hospitalised adult patients with trauma at Mulago national referral hospital
(Makerere University, 2021-04-13)Globally trauma is the leading cause of death in persons aged 5 to 44 years and accounts for approximately 10% of all deaths in general. In Uganda more than 25% of all deaths recorded in urban areas are due to trauma. ...