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Now showing items 21-30 of 36
Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings
(Elsevier, 2008-08)
The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early complication of antiretroviral therapy (ART) in resource-limited settings, especially in patients with tuberculosis. However, there ...
Can response of a pruritic papular eruption to antiretroviral therapy be used as a clinical parameter to monitor virological outcome?
(Lippincott Williams & Wilkins, 2008)
Background: A pruritic papular eruption (PPE) is a common skin manifestation observed in 12–46% of persons with HIV infection living in tropical countries. Objective: To determine whether PPE responds to HAART and whether ...
The liver in HIV in Africa
(International Medical Press, 2005)
As access to antiretroviral therapy improves across the African continent, liver disease is emerging as an important cause of morbidity and mortality among HIV-infected individuals. Although coinfection with hepatitis B ...
Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?
(Open Learning on Enteric Pathogens, 2009-03)
A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient ...
The TB pandemic: an old problem seeking new solutions
(Blackwell, 2007)
Tuberculosis (TB) continues to kill more than 2 million people globally each year. Annual TB case notification rates have risen up to fourfold since the mid-1980s, with the highest rate of 1000/100 000 around Cape Town, ...
Symptomatic hyperlactatemia associated with nucleoside analogue reverse-transcriptase inhibitor use in HIV-infected patients: a report of 24 cases in a Resource-Limited Setting (Uganda).
(University of Chicago Press, 2007-08-15)
We describe 24 Ugandan patients with human immunodeficiency virus infection who developed symptomatic hyperlactatemia associated with the use of nucleoside analogues. All patients were receiving combination therapy that ...
Factors influencing Kaposi's Sarcoma treatment outcome at Uganda Cancer Institute
(2008-07)
Uganda commonly diagnoses epidemic as well as endemic Kaposi's sarcoma cancer variants. A retrospective chart review of 1,483 Kaposi's sarcoma patient files for patients managed at Uganda Cancer institute in Mulago Referral ...
Update on the efficacy, effectiveness and safety of artemether–lumefantrine combination therapy for treatment of uncomplicated malaria
(Dove Medical Press, 2009)
Artemether–lumefantrine is one of the artemisisnin-based combination therapies recommended for treatment of uncomplicated falciparum malaria. The drug combination is highly efficacious against sensitive and multidrug ...
Determination of Lamivudine, Zidovudine, and Nevirapine in capillary blood sampled on filter paper by LC
(Oxford University Press, 2009-11)
A bioanalytical method for determination of lamivudine (3TC), zidovudine (AZT), and nevirapine (NVP) in 100 μL capillary blood applied onto sampling paper has been developed and validated. The antiretroviral drugs (ARV) ...
Developing standard methods to monitor adherence to antiretroviral medicines and treatment defaulting in resource-poor settings
(2009)
Adherence to antiretrovirals is critical for longterm effective therapy with first-line medicines.This important study describes how groups from the International Network for the Rational Use of Drugs in East Africa developed ...