Browsing School of Medicine (Sch. of Med.) Collections by Author "Opoka, Robert O."
-
Cerebral malaria in children is associated with long-term cognitive impairment
Chandy, C. John; Bangirana, P.; Byarugaba, Justus; Opoka, Robert O.; Idro, Richard; Jurek, Anne M.; Wu, Baolin; Boivin, Michael John (2008)OBJECTIVE. Cerebral malaria affects 785 000 African children every year. We previously documented an increased frequency of cognitive impairment in children with cerebral malaria 6 months after their initial malaria ... -
Cognitive impairment after cerebral malaria in children: a prospective study
Boivin, Michael J.; Bangirana, Paul; Byarugaba, Justus; Opoka, Robert O.; Idro, Richard; Jurek, Anne M.; Chandy, C. John (American Academy of Pediatrics, 2007-01-15)OBJECTIVE. This study was conducted to assess prospectively the frequency of cognitive deficits in children with cerebral malaria. METHODS. Cognitive testing in the areas of working memory, attention, and learning was ... -
Methods to estimate baseline creatinine and define acute kidney injury in lean Ugandan children with severe malaria: A prospective cohort study
Batte, Anthony; Starr, Michelle C.; Schwaderer, Andrew L.; Opoka, Robert O.; Namazzi, Ruth; Nishiguchi, Erika S. Phelps; Ssenkusu, John M.; John, Chandy C.; Conroy, Andrea L. (BMC, 2020)Background: Acute kidney injury (AKI) is increasingly recognized as a consequential clinical complication in children with severe malaria. However, approaches to estimate baseline creatinine (bSCr) are not standardized in ... -
Neutrophil gelatinase-associated lipocalin is elevated in children with acute kidney injury and sickle cell anemia, and predicts mortality
Batte, Anthony; Menon, Sahit; Ssenkusu, John M.; Kiguli, Sarah; Kalyesubula, Robert; Lubega, Joseph; Berrens, Zachary; Mutebi, Edrisa Ibrahim; Ogwang, Rodney; Opoka, Robert O.; John, Chandy C.; Conroy, Andrea L. (Elsevier, 2022)Urine neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker of acute kidney injury that has been adapted to a urine dipstick test. However, there is limited data on its use in low and-middle-income countries ... -
Reliability of the Luganda version of the Child Behaviour Checklist in measuring behavioural problems after cerebral malaria
Bangirana, Paul; Nakasujja, Noeline; Giordani, Bruno; Opoka, Robert O.; Chandy, C. John; Boivin, Michael J. (BioMed Central, 2009-12-08)Background: No measure of childhood behaviour has been validated in Uganda despite the documented risks to behaviour. Cerebral malaria in children poses a great risk to their behaviour, however behavioural outcomes after ... -
Seizure activity and neurological sequelae in Ugandan children who have survived an episode of cerebral malaria
Opoka, Robert O.; Bangirana, Paul; Boivin, Michael J.; Chandy, C. John; Byarugaba, Justus (African Health Sciences, 2009)Background: Seizures are a common presenting feature in children with cerebral malaria (CM) and neurologic deficits have been described in survivors of CM. However few prospective studies have described the frequency of ... -
Socioeconomic predictors of cognition in Ugandan children: implications for community interventions
Bangirana, Paul; John, C. Candy; Idro, Richard; Opoka, Robert O.; Byarugaba, Justus; Jurek, Anne M.; Boivin, Michael J. (Public Library of Science, 2009)Background: Several interventions to improve cognition in at risk children have been suggested. Identification of key variables predicting cognition is necessary to guide these interventions. This study was conducted to ...