Search
Now showing items 1-4 of 4
Blood and body fluid exposures among surgeons in Mulago hospital
(COSECSA/ASEA, 2011-11)
Background: It is now recognized that health workers are at risk of acquiring infection with hepatitis B virus (HBV), hepatitis C virus (HCV), HIV and other blood borne pathogens through contact with infected blood and ...
Smart, nano-engineered drug (NRTI)-immune conjugates for targeting HIV within reservoirs
(BioMed Central, 2011-07-22)
Background: Infection with HIV, which culminates in the establishment of a latent proviral reservoir, presents formidable challenges for ultimate cure. Building on the hypothesis that ex-vivo or even in-vivo abolition or ...
HIV/AIDS patients display lower relative bioavailability of Efavirenz than healthy subjects
(Adis Data Information BV., 2011)
Background: Pharmacokinetic studies of antiretroviral drugs are often conducted in adult healthy subjects, and the results are extrapolated to HIV/AIDS patients. HIV/AIDS, however, is known to cause morphological and ...
Phenotypic characterisation of activated plasmacytoid dendritic cells among anti-retroviral therapy-naïve Ugandans with chronic HIV-1 clade A or D infection.
(Makerere University, 2011)
Plasmacytoid dendritic cells (pDC) are the most potent producers of interferon alpha (IFN-α) and tumor necrosis factor alpha (TNF-α) in response to enveloped viruses providing a critical link between the innate and adaptive ...