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T cell Expression of CD153 in Latent Tuberculosis Infection and Type 2 Diabetes Mellitus
(Makerere University, 2022-06-22)
The increasing prevalence of latent tuberculosis among individuals with type 2 diabetes mellitus has increased the public health importance of TB and non-communicable diseases, yet the immune correlates of protection or ...
Use of natural killer cell based assays to assess response to isoniazid preventive therapy among Type 2 Diabetes patients with latent tuberculosis
(Makerere University, 2022-12)
Background: Despite the presence of latent tuberculosis treatment such as Isoniazid treatment therapy, a quarter of the global population remains latently infected with the numbers expected to increase. There is also an ...
Detection of mycobacterium tuberculosis complex DNA in CD34 positive versus CD34-Negative peripheral blood mononuclear cells and the determinants of IGRA positivity in latent Tuberculosis
(Makerere University, 2023)
Background
Tuberculin skin test (TST) and interferon gamma release assay (IGRA), currently used to diagnose latent
tuberculosis infection (LTBI) have low positive predictive values for progression to active tuberculosis ...