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Now showing items 11-19 of 19
Carbapenemase producing Enterobacterieceae carriage among health care workers in selected units of Mulago national referral hospital and Uganda heart institiute
(Makerere University, 2018-10)
Background:Antimicrobial resistance is a global public health concern contributing to increased morbidity and mortality particularly in low income countries where infection control is often inadequate. Multidrug-resistant ...
PREVALENCE OF VIROLOGICAL SUPPRESSION AND PATTERNS OF ACQUIRED HIV DRUG RESISTANCE AMONG INDIVIDUALS ON FIRST-LINE ANTIRETROVIRAL THERAPY IN FISHERFOLK COMMUNITIES IN UGANDA
(2018-10-03)
Background: The UNAIDS targets sustained viral suppression among at least 90% of HIV individuals on antiretroviral therapy (ART), yet viral load (VL) monitoring is rarely done in resource-limited settings due to high costs. ...
Long term non-progressor-derived CD4+ T Cell In-Vitro susceptibility to HIV-1 infection
(Makerere University, 2018-09-01)
Introduction: World over, there are antiretroviral therapy naïve individuals infected with HIV who maintain their CD4+T cell count above 500 cells/μl over 7-10 years (termed as Long Term Non-progressors, LTNP). A subset ...
Role of integrons in dissemination of carbapenem resistance among pseudomonas aeruginosa and acinetobacter baumanii at Mulago Hospital
(Makerere University, 2018)
Background: Carbapenem Resistance emergence threatens effective antimicrobial therapy of infections involving carbapenemase producing Gram negative bacteria especially Pseudomonas aeruginosa and Acinetobacter baumannii. ...
P53 protein expression in nephroblastoma and its association with different histological types and components as seen in the Department of Pathology, Makerere University Kampala, Uganda
(Makerere University, 2018-08)
Background:
Wilms’ tumour is one of the common solid tumours of childhood with an incidence of
approximately 1 in 10,000 children. It is highly responsive to chemotherapy and carries overall good prognosis. However, 10 ...
Prevalence of phenotypic pyrazinamide resistance and agreement with PNCA mutations in mycobacterium tuberculosis isolated from the national drug resistance survey in Uganda, 2008-2011.
(Makerere University, 2018-12-06)
Background: Pyrazinamide (PZA) is a pro-drug with high sterilizing effect used to treat both susceptible and multi-drug resistant tuberculosis. PZA susceptibility testing is not commonly done in Uganda because it is expensive ...
The sputum microbiome composition in pulmonary TB patients and its changes through TB treatment.
(Makerere University, 2018-12-02)
Background: Commensal microbiota residing in or on the human body play key roles in maintaining health and immunity. The abundance and dynamics of these microbial communities when disrupted can result in dysbiosis and the ...
Effects of Mycobacterium tuberculosis on B cell responses.
(Makerere University, 2018-11-04)
Background
Mycobacterium tuberculosis (M.tb) causes tuberculosis (TB), the leading cause of death from a single pathogen. The success of this microbe has been linked to its subversive effects on host immunity. Indeed, ...
Activity and dermal safety of Citrus limon (L.) Burm. f oil from Soroti, Uganda against selected Gram positive and Gram-negative bacteria.
(Makerere University, 2018-08-02)
Background: Essential oils are widely used for culinary and nonculinary purposes like nutraceuticals, traditional medicine, aromatherapy and cosmetics. Genus citrus of the Rutaceae family has several plants including Citrus ...