Browsing School of Bio-Medical Sciences (Bio-Medical) Collections by Subject "Biomarker"
Now showing items 1-4 of 4
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EVALUATION OF CD27 EXPRESSION AS A POTENTIAL BIOMARKER TO DISCRIMINATE ACTIVE FROM LATENT TUBERCULOSIS
(2017-11-16)There is no Gold standard test that can be used to differentiate Latent Tuberculosis Infection (LTBI) from Active Tuberculosis (ATB) with the current tests available. We investigate the use of CD27 expression on CD4 T cells ... -
Heme Oxygenase-1 and Neopterin Plasma Levels and their role in Distinguishing Active from Latent TB among HIV/TB Co-Infected Patients
(Makerere University, 2019-10-18)Background: Tuberculosis(TB) diagnosis in the presence of HIV co-infection remains challenging. Heme oxygenase 1(HO-1) and neopterin have shown to be as potential biomarkers for TB diagnosis. Infection of macrophages with ... -
A metabolic biosignature of early response to anti-tuberculosis treatment
(BMC Infectious Diseases, 2014)Background: The successful treatment of tuberculosis (TB) requires long-term multidrug chemotherapy. Clinical trials to evaluate new drugs and regimens for TB treatment are protracted due to the slow clearance of Mycobacterium ... -
Utility of urine LAM Biomarker for treatment response monitoring during 8 weeks of MDR-TB treatment at Mulago National Referral Hospital
(Makerere University, 2022-03)Background: The current methods used in monitoring treatment response among MDR - TB patients have low sensitivity, take long to give results, are expensive and require BSL3 facilities. It is known that MTB LAM as a biomarker ...