• Login
    View Item 
    •   Mak IR Home
    • College of Health Sciences (CHS)
    • School of Medicine (Sch. of Med.)
    • School of Medicine (Sch. of Med.) Collections
    • View Item
    •   Mak IR Home
    • College of Health Sciences (CHS)
    • School of Medicine (Sch. of Med.)
    • School of Medicine (Sch. of Med.) Collections
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Frequency of and risk factors for HIV dementia in an HIV clinic in sub-Saharan Africa

    Thumbnail
    View/Open
    Wong-chs-res.pdf (325.1Kb)
    Date
    2007
    Author
    Wong, M. H.
    Robertson, K.
    Nakasujja, N
    Skolasky, R.
    Musisi, S.
    Katabira, E.
    McArthur, J. C.
    Ronald, A.
    Sacktor, N.
    Metadata
    Show full item record
    Abstract
    Objective: To measure the frequency and associated risk factors of HIV dementia in an HIV clinic in Kampala, Uganda. Methods: We systematically sampled 78 HIV-seropositive (HIV ) patients from an ambulatory HIV clinic. Participants underwent detailed sociodemographic, medical history, functional, neurologic, and neuropsychological evaluations. One hundred HIV-negative patients were recruited to provide normative data for the neuropsychological tests. A logistic regression model was constructed to determine risk factors associated with the diagnosis of HIV dementia. Results: Thirty-one percent (24 of 78) of the HIV patients had HIV dementia. Advanced age and low CD4 T-lymphocyte count (CD4 count) were the only variables identified as significant risk factors in the logistic regression model. Each additional 10 years of age conferred a greater than twofold risk of HIV dementia (OR 2.06, 95% CI: 1.05 to 4.07; p 0.05). Reduced levels of CD4 count (100 cells/ L decrement) was associated with a 60% increase in the odds of having HIV dementia (OR 1.6, 95% CI: 1.04 to 2.33; p 0.05). Conclusion: HIV dementia is common in HIV-seropositive Ugandan individuals attending an AIDS clinic. It is more frequently associated with patients of advanced age and decreased CD4 count.
    URI
    http://www.neurology.org/cgi/content/full/68/5/350
    http://hdl.handle.net/10570/927
    Collections
    • School of Medicine (Sch. of Med.) Collections

    DSpace 5.8 copyright © Makerere University 
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of Mak IRCommunities & CollectionsTitlesAuthorsBy AdvisorBy Issue DateSubjectsBy TypeThis CollectionTitlesAuthorsBy AdvisorBy Issue DateSubjectsBy Type

    My Account

    LoginRegister

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    DSpace 5.8 copyright © Makerere University 
    Contact Us | Send Feedback
    Theme by 
    Atmire NV