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Metagenomic analysis of coronaviruses in bat fecal matter collected from a human-bat interface around Arua City, West Nile Region, Uganda
(Makerere University, 2022-10)
Background
Many recent disease outbreaks in humans had a zoonotic virus etiology. The ongoing coronavirus disease 2019 (COVID-19) pandemic has had devastating health and socioeconomic impacts. Bats are reservoirs for a ...
Development of an in- house IgM and IgG ELISA for detection of exposure to SARS-COV2
(Makerere University, 2022-12)
Background: Coronavirus disease of 2019 (COVID-19), proved a fatal respiratory disease and
affected millions globally. Due to the faster transmission nature of the virus and any other
predicted forms of viral mutations, ...
Comparison of the performance of RNA extraction kits used in the diagnosis of COVID-19 against TRIZOL-the gold standard for RNA extraction
(Makerere University, 2022-12)
Background: During the COVID-19 pandemic, the Test-Trace-Isolate-Quarantine (TTIQ) strategy was used to break chains of transmission. Diagnosis is a key step in this strategy, and it is done using various RNA extraction ...
Early cytokine profiles associated with mild and asymptomatic COVID-19 disease severity in Uganda
(Makerere University, 2022-12-20)
Emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) constituted a global health threat of highly impactful and pandemic proportions. However, low COVID-19 disease severity was observed in Uganda ...
Evaluation of pre-existing cross reactive cellular immune responses to SARS-CoV-2 in Uganda
(Makerere University, 2022-12)
Background: A low severity of COVID-19 disease has been reported in the Africa population more so in Uganda as compared to other regions like Europe, America and West Pacific. Over 169,996 people have been infected with ...