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Viral load and reverse transcriptase drug resistance mutations in HIV-1 isolated from mothers who transmit the virus to their infants at Kibagabaga Hospital PMTCT Clinic, Kigali, Rwanda
(Makerere University, 2014-09)
Mother to Child Transmission (MTCT) of HIV is the largest source of HIV infection in children below the age of 15 years, affecting five-million infants per year. HIV/AIDS is a disease with known modes of transmission and ...
Tenofovir related renal toxicity monitoring in antiretroviral therapy (ART) accredited sites: A situational analysis for Uganda
(Makerere University, 2014-09)
Background: In Uganda, Tenofovir-based regimen is recommended as first line particularly for HIV/AIDS adult and adolescent patient and for option B+ in prevention of mother-to-child transmission (PMTCT). As a result of ...
Growth patterns and survivability of the different mycobacterium tuberculosis sub lineages predominant in peri urban Kampala
(Makerere University, 2014-05)
Background: Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis (TB) infects over 2 billion people world-wide with the vast majority of deaths from TB in the developing world. Strains of MTB vary in ...
Rhomboids of mycobacteria: insight from phylogeny, genomic and complementation analysis.
(Makerere University, 2014)
Background
The rhomboid superfamily of proteins includes novel trans-membrane Serine-proteases that occur in all life-kingdoms, and are responsible for vital roles such as signaling in Drosophila, red blood cell invasion ...