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Differential prevalence of transporter polymorphisms in symptomatic and asymptomatic Falciparum Malaria Infections in Uganda
(Journal of Infectious Diseases, 2014)
We explored associations between Plasmodium falciparum drug resistance–mediating polymorphisms and clinical presentations in parasitemic children enrolled in a cross-sectional survey in Tororo, Uganda, using a retrospective ...
Quality of Sulfadoxine-pyrimethamine (SP) tablets sold in drug outlets in Arua District, Uganda
(Makerere University, 2010-09)
Background: Sulfadoxine-pyrimethamine (SP) remain a corner stone in intermittent preventive treatment (IPT) of malaria in pregnancy. Reports of substandard and counterfeit antimalarial drugs in Uganda and neighbouring ...
The effect of consuming groundnut (Arachis Hypogaea) on serum testosterone levels and lipid profile in male rats
(Makerere University, 2011-11)
Introduction: Groundnuts (Arachis hypogaea) have been used by people for nutritional, medicinal, and recreational purposes. Researchers have reported groundnuts being rich in nutrients such as zinc, monounsaturated fats ...
Bacteriological quality analysis of herbal cosmetics sold in Kampala District, Uganda
(Makerere University, 2011-07)
The use of herbal cosmetics is popular in Uganda. Despite the increase in consumer trust for these products, the bacteriological quality of herbal cosmetics sold in Kampala has remained unknown. Regulatory polices on herbal ...
Human pelvis height is associated with other pelvis measurements of obstetric value.
(Association of Anatomical Societies of Africa, 2015)
In low resource settings, perinatal death remains a major challenge, yet some of the key
anthropometric measures used for screening have been found to be inappropriate. These calls for
additional anatomically related ...
Cotrimoxazole Prophylaxis specifically selects for Cotrimoxazole resistance in Streptococcus mutans and Streptococcus sobrinus with varied Polymorphisms in the target genes folA and folP
(Hindawi Publishing Corporation, International Journal of Microbiology, 2012)
The selection of antibiotic resistance by cotrimoxazole prophylaxis was evaluated, and we characterized the mechanism of cotrimoxazole resistance in Streptococcus mutans and Streptococcus sobrinus. In vitro susceptibility ...
Prevalence and factors associated with intestinal helminths infestation and schistosoma mansoni among residents of Katosi fish landing site in Mukono District, Uganda
(Makerere University, 2012-06)
Introduction: It is estimated that over one billion of the world’s population is chronically infested with intestinal helminths and these infestations are closely correlated to poverty, poor environmental hygiene and poor ...
Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing
(PLOS One, 2013)
Background: Understanding the emergence and spread of multidrug-resistant tuberculosis (MDR-TB) is crucial for its control. MDR-TB in previously treated patients is generally attributed to the selection of drug resistant ...
Meta-analysis to compare the accuracy of GeneXpert, MODS and the WHO 2007 algorithm for diagnosis of smear-negative pulmonary tuberculosis
(BMC Infectious Diseases, 2013)
Background: Smear-negative pulmonary tuberculosis (SN-PTB), which is common in HIV-infected patients, is difficult to diagnose using smear microscopy alone. In 2007, the WHO developed an algorithm to improve the diagnosis ...
How reliable are hematological parameters in predicting uncomplicated plasmodium falciparum malaria in an Endemic Region?
(Hindawi Publishing Corporation, 2013)
Background. Malaria remains endemic in Sub-Saharan Africa. Hematological changes that occur have been suggested as potential predictors of malaria. This study was aimed at evaluating the diagnostic relevance of hematological ...