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DEVELOPMENT AND OPTIMIZATION OF AN IN VITRO METHOD TO FORCE AND SELECT FOR FUNCTIONAL HIV-1 INTERSUBTYPE pol RECOMBINANTS
(Makerere University, 2019-10-22)
Introduction
Inter subtype recombination in the pol gene of the HIV-1 affects the enzymatic structure and
integrity which greatly impacts their function. These may be silent, deleterious or beneficial for
the survival ...