Use of stored serum from Uganda for development and evaluation of Human Immunodeficiency Type 1 Testing Algorithm involving Multiple Rapid immunoassays
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Date
2005-10Author
Singer, D. E.
Kiwanuka, Noah
Serwadda, David
Nalugoda, Fred
Hird, Linda
Bulken-Hoover, Jamie
Kigozi, Godfrey
Malia, Jennifer A.
Calero, Eva K.
Sateren, Warren
Robb, Merlin L
Wabwire-Mangen, Fred
Wawer, Maria
Gray, Ronald H.
Sewankambo, Nelson
Birx, Deborah L.
Michael, Nelson L.
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We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).