College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 2946
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Health-related quality of life among adult patients with cancer in Uganda – A cross-sectional study
(Taylor & Francis, 2024)Objectives: The study aimed to investigate the prevalence and factors associated with poor health-related quality of life in adults with cancer in Uganda. Methods: This cross-sectional study surveyed 385 adult patients ... -
Detection of clinically relevant respiratory viruses and their temporal dynamics in sputum of tuberculosis patients on anti-TB drugs at Naguru Hospital, Kampala, Uganda
(Makerere University, 2024)Background Tuberculosis is one of the leading infectious causes of death in the world, with nearly 10 million new cases diagnosed each year, resulting into an estimated 1.3 million deaths(1). The relationship between M. ... -
Factors associated with incomplete COVID-19 vaccination among healthcare workers in Kampala Capital City Health Facilities. An explanatory sequential mixed methods study
(Makerere University, 2024)Introduction: Health workers involved in rapid response to viral infectious disease outbreaks like Ebola, Marburg among others are almost certainly at an increased risk of acquiring infection compared to the public. Like ... -
Antimicrobial stewardship practices and quality of antibacterial use in children under five and women in labour with obstetric risk factors in selected health facilities in Uganda
(Makerere University, 2024)Introduction Bacterial infections are a leading cause of morbidity and mortality in Ugandan hospitalised children under the age of five. Disparities exist in using antibacterial agents to treat bacterial infections at ... -
Prevalence, factors associated and outcomes of critical illness among high-risk postpartum mothers at a Ugandan tertiary hospital. A prospective observational study
(Makerere University, 2023)Background: Despite improving trends, there remains a high global burden of maternal mortality, which is almost invariably preceded by some form of critical illness. Timely recognition and appropriate intervention may ... -
Uptake and factors associated with uptake of human papillomavirus vaccination among adolescent girls aged 13-18 years seeking health services at Kiswa Health Center III
(Makerere University, 2023)Background: HPV is a highly prevalent sexually transmitted infection with a significant role in the cause of cervical cancer. In Uganda, the cervical cancer age-standardized incidence rate is estimated to be 56.2 per 100,000 ... -
Detection of mycobacterium tuberculosis complex DNA in CD34 positive versus CD34-Negative peripheral blood mononuclear cells and the determinants of IGRA positivity in latent Tuberculosis
(Makerere University, 2023)Background Tuberculin skin test (TST) and interferon gamma release assay (IGRA), currently used to diagnose latent tuberculosis infection (LTBI) have low positive predictive values for progression to active tuberculosis ... -
Access to improved sanitation among households in peri urban area in Bwaise II Parish, Kawempe Division: A cross sectional study
(Makerere University, 2023)Introduction: Sustainable Development Goal (SDG) target 6.2 aims at achieving universal access to sanitation, leaving no one behind by 2030. To enhance this achievement, SDG target 1.4 aims at basic sanitation for all ... -
Costs of tuberculosis care and associated factors among patients with HIV or diabetes mellitus comorbidities attending selected health facilities in Kampala from a societal perspective
(Makerere University, 2023)Introduction In Uganda, the Tuberculosis (TB) burden among Human immunodeficiency virus (HIV) patients is still high and increasing significantly among DM patients due to the looming DM epidemic. Although TB drugs and ... -
Factors associated with virological non-suppression among adult HIV clients with low-level viremia in Kampala, Uganda
(Makerere University, 2022)The goal of antiretroviral therapy is to maximize the inhibition of infectious virion production to below the level of detection of less than 50 copies/ml. Clients with LLV have not been fully studied in Uganda and ... -
Effect of perioperative blood transfusion on complications following emergency non-trauma laparotomy: A prospective cohort study
(Makerere University, 2024)Introduction: Blood transfusion may be required in the management of patients undergoing emergency non-trauma laparotomy. However, retrospective cohort studies involving patients undergoing emergency laparotomy have ... -
Evaluating readiness for implementation of the eight antenatal care contacts as per the World Health Organization guidelines in Bukwo District, Uganda
(Makerere University, 2023)Background: Low and Middle Income Countries (LMICs) account for around 99 % of maternal deaths worldwide, with Sub-Saharan Africa (SSA) responsible for about 66 % of these demises. The new Antenatal Care (ANC) model with ... -
A machine learning approach to predict E. coli antibacterial resistance using whole-genome sequencing data
(Makerere University, 2023)Background: Antimicrobial resistance (AMR) is a significant global health threat, particularly impacting low- and middle-income countries(LMICS) such as Uganda, where reliable and rapid methods for detecting AMR in E. coli ... -
Uptake of preventive nutrition interventions among caretakers of children under 5 years in a pastoral setting of South Sudan: A case of Kapoeta South County
(Makerere University, 2023)Background: Preventive nutrition interventions are usually implemented without understanding how multiple factors affect uptake. Pastoralist populations have shown low uptake. A multidimensional study of uptake in the ... -
Health related quality of life and associated factors of post-pulmonary tuberculosis lung disease patients treated from Mulago National Referral Hospital, Kampala - Uganda
(Makerere University, 2024)Introduction: By the end of 2020, there were approximately 155 million TB survivors globally. TB survivors have up to three times increased risk of mortality from post-Pulmonary TB lung complications compared with the ... -
Exploring the under reporting of pregnancy and adverse pregnancy outcomes in population and health surveys : a multi-country qualitative study
(Makerere University, 2023)Introduction: Globally in 2021, an estimated 2.3 million newborn deaths and 1.9 million stillbirths occurred, with highest mortality in sub-Saharan Africa and southern Asia. True mortality is likely higher due to under ... -
Transcriptome analysis of micro-RNAs associated with COVID-19 disease
(Makerere University, 2023-11)The host microRNA (miRNA), which is essential for maintaining the epithelial cell barrier in the respiratory tract as well as controlling viral entry and reproduction, plays a significant role in COVID-19 infection. ... -
Knowledge attitudes and practices towards premarital medical examination among young unmarried people aged 18-49 years in Lyantonde District, Uganda
(Makerere University, 2024)Introduction: Undergoing Premarital Medical Examination (PME) helps couples to ascertain the compatibility of their health status and the likelihood of producing healthy offspring prior to their marriage decisions. This ... -
Examining the gaps and barriers in monitoring and evaluation of male engagement in family planning among selected Non-governmental organizations in the health sector in Kampala Capital City Authority, Uganda
(Makerere University, 2023)Male engagement in reproductive health/family planning is considered an integral component in maximizing reproductive health outcomes. However, monitoring and evaluation efforts towards this approach is significantly low, ... -
Factors associated with infant and young child feeding practices among mothers of children 0-23 months attending Banadir Hospital in Wadajir District, Somalia
(Makerere University, 2023)Understanding the prevailing feeding practices of infants and young children is crucial for implementing or improving health and nutrition programs in a country. In Somalia, the prevalence of Malnutrition is high. The ...