College of Health Sciences (CHS): Recent submissions
Now showing items 21-40 of 3269
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CD133 protein expression in primary liver cancer; associated demographic and histopathological characteristics in Uganda
(Makerere University, 2024)Primary liver cancer is a leading cause of cancer morbidity and mortality. Globally, it is the 6th most common cancer and the 3rd most common cause of cancer deaths. In Uganda, liver cancer is the 7th most common cancer ... -
Factors associated with COVID-19 vaccine uptake in the slums of Kawempe Division, Kampala District
(Makerere University, 2024)Although the World Health Organization recommended vaccination as the most effective way to prevent novel coronavirus disease (COVID-19), uptake of COVID-19 vaccines remains suboptimal in low-income countries such as Uganda. ... -
A semantic interoperability framework for contextualising common standards supporting health information exchange in Uganda's healthcare ecosystem
(Makerere University, 2024)Introduction: Uganda’s healthcare system faces challenges of fragmented data systems, inadequate infrastructure, and limited resources, hindering effective information exchange and care coordination. More than 50 digital ... -
A genome-wide association study of blood urea nitrogen levels in the Uganda Genome Resource Cohort
(Makerere University, 2024)Blood urea nitrogen (BUN) is a key biomarker of kidney function, reflecting the balance between urea production and excretion. Elevated BUN levels are associated with impaired kidney function and serve as a diagnostic and ... -
Factors associated with hospital-acquired diarrhea among children (0-59 months) with severe acute malnutrition at Mwanamugimu Nutrition Unit, Mulago National Referral Hospital, Kampala District
(Makerere University, 2024)Introduction: Hospital-acquired diarrhea remains a major global public health concern and is one of the leading causes of morbidity and mortality among children with severe acute malnutrition. In Uganda, Hospital acquired ... -
Understanding the facilitators and barriers to dog mass vaccination campaigns in Uganda, A case of Kyegegwa District
(Makerere University, 2024)Background: Despite the annual commitment to procure 500,000 rabies vaccine doses and distributing them to districts freely on request, Uganda still grapples with a low dog vaccination coverage of about 10%. This study ... -
Assessing comprehension of informed consent among research participants enrolled in a malaria prevention study at Masafu Hospital, Busia District
(Makerere University, 2024)Introduction: Comprehension of informed consent by research participants is a fundamental pillar of the informed consent process. Participants quite often have low comprehension of medical procedures, risks and complications. ... -
Newborn care practices in Nakapiripirit District, North Eastern Uganda: A community-based cross-sectional study
(Makerere University, 2024)Introduction: Despite improved health facility deliveries in Uganda, the neonatal mortality rate has only improved marginally over the last three decades. Karamoja region in North-Eastern Uganda has one of the poorest ... -
Isoniazid hair drug levels among drug-susceptible pulmonary tuberculosis patients: A study to monitor exposure, adherence and treatment outcomes
(Makerere University, 2024)Background: Tuberculosis (TB) is still a major public health problem globally and in Uganda.Therapeutic drug monitoring (TDM) for TB improves treatment outcomes and mitigates the emergence of drug resistance (DR). Despite ... -
Enablers and barriers to adoption of the recommended infant feeding practices among primary caregivers with infants and young children in BidiBidi Refugee Settlement, Yumbe District
(Makerere University, 2024)Introduction Infant and Young Child Feeding (IYCF) practices are vital for reducing childhood morbidity and mortality. Globally, only about 42 percent of women begin breastfeeding within the first one hour of birth, 41% ... -
Evaluation of the performance of the newborn sickle cell screening program and associated facilitators and challenges in Uganda
(Makerere University, 2024)Introduction In Africa, scaling up of national screening programs has been shown to be difficult. This could be attributed to the various challenges facing these programs in Africa. Therefore, is important to monitor ... -
Phenotypic characterization of bacterial species associated with periodontitis among patients attending Makerere, Mengo and Mulago Paramedical Dental Clinics in Kampala, Uganda
(Makerere University, 2024)Periodontitis is a prevalent dental disease often linked to bacterial infections, leading to inflammation and the deterioration of tissues supporting the teeth. The disease caused by pathogenic microbes forming biofilms ... -
Time from recognition of symptoms to cancer diagnosis and factors associated with delayed diagnosis among pediatric cancer patients in Mulago National Referral Hospital
(Makerere University, 2024)Introduction: Late presentation of pediatric cancers is common in sub- Saharan African countries, including Uganda and is largely due to diagnosis delay; a combination of patient/caregiver delay and physician/ health system ... -
Household parental alcoholism and the nutritional status of children aged 6-59 months in Kyegegwa Sub-County, Kyegegwa District, Uganda
(Makerere University, 2024)Background: Families with parental alcoholism are characterized by significantly lower socioeconomic status negatively affecting the nutritional status of their under five years children compared to other household members. ... -
Prevalence of diarrhea and associated factors among children under 5 years in Bugiri District, Uganda
(Makerere University, 2024)Diarrhoea remains a significant public health concern globally, particularly affecting children under five years, predominantly in resource-limited settings. This study investigated the prevalence of diarrhoea and associated ... -
Modelling recurrent complications among children with advanced HIV disease using conditional survival analysis models
(Makerere University, 2024)Infants and young children infected with HIV face higher morbidity & mortality rates. Children under five with HIV are considered to have advanced HIV disease. Common causes of death in these patients include TB, severe ... -
Role of killer cell immunoglobulin-like receptors in the functional modulation of NK cell response to HIV-1 viral reservoirs in individuals on antiretroviral therapy
(Makerere University, 2024)Sub-Saharan Africa has two thirds of the global population living with HIV. Uganda has one of the highest burdens of HIV/AIDS globally, with a significant proportion of individuals on antiretroviral therapy. Complete ... -
Exposure to laboratory hazards and associated factors among learners in secondary schools in the greater Kampala Metropolitan Area, Uganda
(Makerere University, 2024)Global, regional, and local agendas are striving to promote Science Technology and Innovation which requires safe learning environments such as laboratories. Laboratory safety remains a growing occupational health and ... -
Iodine status and associated factors among pregnant women attending antenatal care at four selected health facilities in Kasese District
(Makerere University, 2024)Background: Pregnancy increases the iodine dietary requirements to meet the needs of the mother and the baby. Both iodine deficiency and excessive iodine are known to cause fetal and maternal thyroid disease. Uganda lacks ... -
Using machine learning and sequential characteristics in prediction of cardiac arrest: a case study of Uganda Heart Institute, Central Uganda
(Makerere University, 2024)Background: Research on cardiac arrest and its associated risk factors has considerably increased in recent decades. With that, several machine learning models have been implemented to predict the onset of cardiac arrest ...