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HIV/AIDS patients display lower relative bioavailability of Efavirenz than healthy subjects
(Adis Data Information BV., 2011)
Background: Pharmacokinetic studies of antiretroviral drugs are often conducted in adult healthy subjects, and the results are extrapolated to HIV/AIDS patients. HIV/AIDS, however, is known to cause morphological and ...
Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
(Lippincott Wilkins & Williams, 2011)
Background: Tuberculosis-HIV (TB-HIV) coinfection remains an
important cause of mortality in antiretroviral therapy (ART)
programs. In a cohort of TB-HIV–coinfected patients starting
ART, we examined the incidence and ...
Quantitative assessment of the sensitivity of various commercial reverse transcriptases based on armored HIV RNA
(Public Library of Science, 2010)
Background: The in-vitro reverse transcription of RNA to its complementary DNA, catalyzed by the enzyme reverse transcriptase, is
the most fundamental step in the quantitative RNA detection in genomic studies. As such, ...
Prevalence of HIV/AIDS among breast cancer patients and the clinico-pathological presentation of breast cancer with HIV/AIDS in Mulago Hospital
(Makerere University, 2011-04)
Background: Breast cancer is the most common site-specific cancer accounting for 33% of all female cancers and is responsible for 20% of the cancer-related deaths in women.
Objective: To determine the prevalence of HIV ...
Factors associated with male involvement in prevention of mother to child transmission of HIV (PMTCT) programmes in Entebbe Municipality
(Makerere University, 2012)
Background: Involving men in PMTCT programmes increases its uptake by women. Despite this observation, providers and implementers of PMTCT programmes continue to face challenges in reaching sexual partners of HIV positive ...
Non-linear mixed effects modeling of liver function biomarkers in TB-HIV patients co-treated with Rifampicin and Efavirenz based regimens
(2013-11)
Introduction
Survival has improved as a result of improved HIV therapy but liver disease remains a critical problem in HIV patients. HIV disease, ART and Tuberculosis treatments have all been documented to cause liver ...
Prevalence and factors associated with use of traditional medicine among HIV positive clients in Mubende District, Uganda
(2012-03)
Introduction: Traditional Medicine is widely used in Uganda and Sub-Saharan African in general.There are proven adverse interactions between some herbal medications and ARV drugs hence the practice of concurrent use of the ...
Marriage, Risk Behaviours and HIV Infection in Rural Rakai, South Western Uganda
(Makerere University, 2014-10)
The HIV/AIDS epidemic is still a global problem that is most severe in sub-Saharan Africa. It is estimated that over 2.1 million (1.9 – 2.7 million) people became newly infected with HIV in 2012 year (UNAIDS, 2013 and 70% ...
CDd4 t- cell immune responses in haart-treated hiv-infected adults who attain normal CD4 counts in a Ugandan cohort
(Makerere University, 2014-05)
Background: Majority of HIV-infected individuals who start HAART at CD4 counts <200 cells/µl show a marked CD4+T-cell increase to absolute CD4 counts above 500 cells/µl. The CD4+ T-cell count is the main measure for immune ...
Uptake of cervical screening and prevalence of abnormal cervical lesions among HIV infected women in an urban HIV care setting in Uganda
(Makerere University, 2014)
Background: Cervical cancer is the second commonest cancer in women worldwide and the commonest cancer among women in Uganda. Annual cervical screening is recommended for women living with HIV for early detection of ...