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Factors influencing coartem uptake of children 6 to 59 months old with umcomplicated malaria in Ntungamo District, Uganda.
(2009)
INTRODUCTION:
Artemisinin based combination therapies are recommended for malaria treatment. In Ntungamo district, only 38% of the children aged 6 to 59 months receive coartem following onset of fever compared to national ...
Local fever illness classifications: implications for home management of malaria strategies
(Wiley-Blackwell, 2004-11)
Background: The Ugandan Ministry of Health has adopted the WHO Home Based Fever Management strategy (HBM) to improve access to antimalarial drugs for prompt (<24 h) presumptive treatment of all fevers in children under 5 ...
Update on the efficacy, effectiveness and safety of artemether–lumefantrine combination therapy for treatment of uncomplicated malaria
(Dove Medical Press, 2009)
Artemether–lumefantrine is one of the artemisisnin-based combination therapies recommended for treatment of uncomplicated falciparum malaria. The drug combination is highly efficacious against sensitive and multidrug ...
Existing capacity to manage pharmaceuticals and related commodities in East Africa: an assessment with specific reference to antiretroviral therapy
(BioMed Central, 2009)
Background: East African countries have in the recent past experienced a tremendous increase in the volume of antiretroviral drugs. Capacity to manage these medicines in the region remains limited. Makerere University, ...
Inpatient mortality in children with clinically diagnosed malaria as compared with microscopically confirmed malaria
(Lippincott Wilkins & Williams, 2008)
Background: Inpatient treatment for malaria without microscopic confirmation of the diagnosis occurs commonly in sub-Saharan Africa. Differences in mortality in children who are tested by microscopy for Plasmodium falciparum ...
Effect of HIV-1 infection on antimalarial treatment outcomes in Uganda: a population-based study.
(University of Chicago Press, 2005-11-18)
Background. Human immunodeficiency virus (HIV) infection may increase the burden of malaria by increasing susceptibility to infection or by decreasing the response to antimalarial treatment. We investigated the seroprevalence ...
Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis
(BioMed Central, 2009-08-23)
Background: Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the efficacy of ACT, recently adopted by the World ...
Treatment of severe sepsis with Artemether-Lumefantrine Is associated with decreased mortality in Ugandan patients without malaria
(The American Society of Tropical Medicine and Hygiene, 2009)
We enrolled 382 patients at two hospitals in Uganda in a prospective observational study of severe sepsis. Because artemisinins improve survival in murine sepsis models, we performed a post hoc analysis of the association ...
Iron status in patients with plasmodium falciparum malaria and anaemia in Mulago hospital
(2002)
Malaria is an important cause of morbidity and mortality in Uganda. It is associated with a wide range of complications including severe anaemia especially in children. Anaemia impairs motor and cognitive development in ...
Medical audit on problem analysis and implementing changes at the health unit level.
(Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa, 2007)
Background: Decentralization is one of the reforms the Uganda government adopted to improve public services delivery. However, human resource numbers and capacities in local governments remain below the required level and ...