Browsing College of Health Sciences (CHS) by Subject "Tuberculosis"
Now showing items 1-20 of 67
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Assessment of the implementation of tuberculosis (TB) communty based directly observed treatemtn, (CB-DOTS), in Tororo District, Uganda
(2007-05)INTRODUCTION AND BACKGROUND: Tuberculosis (TB) affects 20 million people the world over. Uganda is among the 22 high burden countries (HBC) and is ranked 16th in the global TB control. Community based directly observed ... -
Bronchoscopy is useful for diagnosing smear-negative tuberculosis in HIV-infected patients
(European Respiratory Journal, 2010) -
Burden of tuberculosis in Kampala, Uganda
(World Health Organization (WHO), 2008)Objective: To determine the prevalence and incidence of tuberculosis in one of Uganda’s poor peri-urban areas. Methods: Multi-stage sampling was used to select a sample of households whose members were evaluated for presence ... -
Case detection of tuberculosis patients using machine learning : a case study of China Friendship Hospital Naguru, Kampala
(Makerere University, 2021-08-18)Although early detection and treatment of Tuberculosis cases are the hallmark of successful TB control, diagnostic delay is still long and common in Uganda. Therefore, the study aimed at developing a tool that uses ... -
A comparison of sodium hypochlorite n-acetyl-l-cystein sputum concentration methods and culture for diagnosis of smear negative pulmonary tuberculosis suspects attending Mulago hospital.
(2005)The sensitivity of direct sputum smear microscopy is very low, ranging from 25 to 65%. It is thus inevitable that direct smear microscopy needs to be improved or other methods of diagnosis of smear negative (TB) be designed. ... -
Costs of tuberculosis care and associated factors among patients with HIV or diabetes mellitus comorbidities attending selected health facilities in Kampala from a societal perspective
(Makerere University, 2023)Introduction In Uganda, the Tuberculosis (TB) burden among Human immunodeficiency virus (HIV) patients is still high and increasing significantly among DM patients due to the looming DM epidemic. Although TB drugs and ... -
Determinants of health related quality of life in smear positive and smear negative adult tuberculosis patients in Kampala, Uganda
(Makerere University, 2014)Introduction/background: Smear negative Tuberculosis has been on the rise since the HIV epidemic and is associated with poor clinical outcomes. There is limited information regarding health related quality of life(HRQoL) ... -
Developing a theory informed intervention to improve linkage to treatment for patients diagnosed with tuberculosis using XPERT® MTB/RIF testing in Central and Eastern Uganda
(Makerere University, 2022-11)Background: In 2019, Uganda notified only 74% of estimated TB cases against an END TB target of 90%. This gap between estimated incident TB cases and those accessing TB treatment is due to a combination of underdiagnosis ... -
The diagnosis of childhood tuberculosis in an HIV-endemic setting and the use of induced sputum
(International Union Against Tuberculosis and Lung Disease, 2005)Setting: A hospital in the capital city of Uganda. Objectives: To determine the proportion of positive induced sputum cultures among probable childhood tuberculosis (TB) cases, to describe the laboratory and radiological ... -
Digital clubbing in tuberculosis – relationship to HIV infection, extent of disease and hypoalbuminemia
(BioMed Central, 2006-03-10)Background: Digital clubbing is a sign of chest disease known since the time of Hippocrates. Its association with tuberculosis (TB) has not been well studied, particularly in Africa where TB is common. The prevalence of ... -
The effect of AIDS defining conditions on immunological recovery among patients initiating antiretroviral therapy at Joint Clinical Research Centre, Uganda
(BioMed Central, 2009-07-24)Background: Many HIV-infected patients only access health care once they have developed advanced symptomatic disease resulting from AIDS Defining Conditions (ADCs). We carried out a study to establish the effect of ADCs ... -
The effect of bacille Calmette-Guérin vaccination at birth on tuberculin skin test reactivity in Ugandan children
(International Union Against Tuberculosis and Lung Disease, 1999)SETTING: In Uganda, bacille-Calmette Guérin (BCG) vaccination coverage at birth is between 82 and 84%. OBJECTIVE: To evaluate the effect of neonatal BCG vaccination on tuberculin skin test positivity in Ugandan children ... -
Effect of COVID-19 period on tuberculosis treatment success; A mixed methods study among tuberculosis patients at Jinja Regional Referral Hospital
(Makerere University, 2022-01)Introduction: Before the COVID-19 pandemic, over 4000 people were dying from TB every day. TB is still a major public health threat globally, but the TB epidemic may be exacerbated by the COVID-19 pandemic. The lockdown ... -
Effect of vitamin d binding protein gene polymorphisms and vitamin d bioavailability on cathelicidin expression in tuberculosis infection and disease
(Makerere University, 2023-01)Background: The human antimicrobial peptide cathelicidin (LL-37) is involved in host innate immunity by the after activation of Toll-like receptors (TLRs), resulting in direct killing of Mycobacterium tuberculosis (MTB). ... -
Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing
(PLOS One, 2013)Background: Understanding the emergence and spread of multidrug-resistant tuberculosis (MDR-TB) is crucial for its control. MDR-TB in previously treated patients is generally attributed to the selection of drug resistant ... -
Evaluation of suspected tuberculous pleurisy: clinical and diagnostic findings in HIV-1-positive and HIV-negative adults in Uganda
(International Union Against Tuberculosis and Lung Disease, 2001-04)SETTING: National Tuberculosis Treatment Centre, Mulago Hospital, Kampala, Uganda. OBJECTIVES: To compare clinical and radiographic presentation, and diagnostic methods, in adults with tuberculous pleurisy who are negative ... -
Evaluation of the GenoType MTBDRplus v2 Line Probe Assay for Rapid Diagnosis of Multidrug Resistant Tuberculosis in Uganda
(Makerere University, 2014)Introduction: Multidrug-resistant tuberculosis (MDR-TB) poses a major challenge to TB control due to its complex diagnostic and treatment challenges. Globally, 3.7% of new cases and 20% of previously treated cases are ... -
Facilitators and barriers to tuberculosis case notification among private health facilities in Kampala Capital City
(Makerere University, 2022-08)Introduction: The linkage of Private Health Providers (PHPs) is known to improve Tuberculosis (TB) case finding in the fight against the TB epidemic. In Uganda, 58% of people with TB related symptoms seek care initially ... -
Factors affecting use of community based tuberculosis care in kampala district, uganda.
(2007-11)Tuberculosis(T.B)is among the leading causes of mortality and affects one third of the population in the developing countries. Community based tuberculosis short course therapy(CBDOTS) is the most effective strategy available ... -
Factors associated with healthcare workers’ adherence to national guidelines for MDR TB surveillance in Uganda: A case study of the West Nile region
(Makerere University, 2014)Background: A previous history of tuberculosis (TB) treatment has been identified as a risk factor for multidrug resistant TB. Therefore these patients are a high priority group for whom culture and drug-susceptibility ...