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Diagnostic Accuracy and Cost-Effectiveness of Alternative Methods for Detection of Soil-Transmitted Helminths in a Post-Treatment Setting in Western Kenya
(PLOS, 2014)
Objectives: This study evaluates the diagnostic accuracy and cost-effectiveness of the Kato-Katz and Mini-FLOTAC methods
for detection of soil-transmitted helminths (STH) in a post-treatment setting in western Kenya. A ...
Comments on: predictors of immune recovery and the association with late mortalty while on antiretroviral treatment in Cambodia.
(Elsevier, 2012)
We read with great interest the article by van Griensven and Thai, who report on the risk factors for late mortality after antiretroviral therapy (ART) initiation in a cohort of 2840 patients in Cambodia. The main risk ...
Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: A prospective cohort study
(PLoS Medicine, 2010)
Background: Although antiretroviral therapy (ART) improves survival in persons with cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution inflammatory syndrome (IRIS), an exaggerated and ...
Surgical site infections after neurosurgical procedures at Mulago National Referral Hospital; prevalence and bacteriological patterns
(Makerere University, 2017)
Introduction
ABSTRACT
Surgical site infections (SSIs) remain a major cause of morbidity and mortality. They also cause high financial burden in healthcare systems worldwide. The development of postoperative surgical ...
Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV prevalence setting: a prospective cohort study
(Public Library of Science, 2011-01)
Background: Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. ...
Integration of HIV and TB services results in improved TB treatment outcomes and earlier prioritized ART initiation in a large urban HIV clinic in Uganda
(Lippincott, Williams & Wilkins, 2012-06-01)
Background: The World Health Organization recommends that treatment of tuberculosis ...
Rifampicin for continuation phase tuberculosis treatment in Uganda: a cost-effectiveness analysis
(Public Library of Science, 2012-06)
Background: In Uganda, isoniazid plus ethambutol is used for 6 months (6HE) during the continuation treatment phase of new tuberculosis (TB) cases. However, the World Health Organization (WHO) recommends using isoniazid ...
Sub-optimal vitamin B-12 levels among ART-Naïve HIV positive individuals in an urban cohort in Uganda
(Public Library of Science, 2012-07-02)
Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression ...
Pharmacokinetics of antiretroviral drug varies with formulation in the target population of children with HIV-1
(Clinical Pharmacology & Therapeutics (Nature Publishing Group), 2012-02-21)
The bioequivalence of formulations is usually evaluated in healthy adult volunteers. In our study in 19 HIV-1-infected Ugandan children (1.8–4 years of age, weight 12 to <15 kg) receiving zidovudine, lamivudine, and abacavir ...
Pharmacokinetic interactions between antiretroviral drugs and herbal medicines
(British Journal of Hospital Medicine, 2012-03-13)