Browsing School of Medicine (Sch. of Med.) Collections by Subject "Plasmodium falciparum"
Now showing items 1-6 of 6
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Association between indoor residual spraying and pregnancy outcomes: a quasi-experimental study from Uganda
(Oxford University Press, 2022)Background: Malaria is a risk factor for adverse pregnancy outcomes. Indoor residual spraying with insecticide (IRS) reduces malaria infections, yet the effects of IRS on pregnancy outcomes are not well established. We ... -
Associations between aminoquinoline resistance genotypes and clinical presentations of Pplasmodium falciparum Infection in Uganda
(American Society for Microbiology., 2020)Mutations that mediate resistance of Plasmodium falciparum to aminoquinoline antimalarials are selected by prior drug use and may alter parasite fitness, but associations with clinical presentations are uncertain. We ... -
Cerebral malaria in children is associated with long-term cognitive impairment
(2008)OBJECTIVE. Cerebral malaria affects 785 000 African children every year. We previously documented an increased frequency of cognitive impairment in children with cerebral malaria 6 months after their initial malaria ... -
Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisinin combination therapy: complexity of infection during short-term culture and characterization of in vitro sensitivity in Kampala Uganda
(Makerere University, 2010)Background: Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant ... -
Iron status in patients with plasmodium falciparum malaria and anaemia in Mulago hospital
(2002)Malaria is an important cause of morbidity and mortality in Uganda. It is associated with a wide range of complications including severe anaemia especially in children. Anaemia impairs motor and cognitive development in ... -
A quasi-experimental study estimating the impact of long-lasting insecticidal nets with and without piperonyl butoxide on pregnancy outcomes
(BMC, 2022)Background: Long-lasting insecticidal nets (LLINs) are the main vector control tool for pregnant women, but their efficacy may be compromised, in part, due to pyrethroid resistance. In 2017, the Ugandan Ministry of Health ...