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Effect of HIV-1 infection on malaria treatment outcome in Uganda patients
(Makerere University Medical School, 2007)
Background: Malaria and HIV-1 infection cause significant morbidity and mortality in sub-Saharan Africa. HIV-1 increases risk for malaria with the risk increasing as immunity declines. The effect of HIV-1 infection on ...
Discontinuation and modification of Highly Active Antiretroviral Therapy in HIV-infected Ugandans prevalence and associated factors.
(Lippincott Williams & Wilkins, 2007-03-16)
Background: Data on discontinuation and modification of highly active antiretroviral therapy (HAART) are scarce among sub-Saharan African populations. We sought to estimate the prevalence and to identify factors associated ...
Severe sepsis in two Ugandan hospitals: a prospective observational study of management and outcomes in a predominantly HIV-1 infected population
(Public Library of Science, 2009-11-11)
Background: Sepsis likely contributes to the high burden of infectious disease morbidity and mortality in low income countries. Data regarding sepsis management in sub-Saharan Africa are limited. We conducted a prospective ...
Tuberculosis in household contacts of infectious cases in Kampala, Uganda
(2003)
Tuberculosis remains a serious threat to public health, especially in sub-Saharan Africa. To determine the host and environmental factors responsible for tuberculosis in African households, the authors performed a prospective ...
Strategies to optimize HIV treatment outcomes in resource-limited settings
(Permanyer Publications, 2009)
Although the availability of antiretroviral therapy has increased rapidly to reach over three million people in low- and middle-income countries, coverage remains low as only 31% of people in need were receiving antiretroviral ...
Effect of home based water chlorination and safe storage on diarrhea among persons with human immonodeficiency virus in Uganda.
(American Society of Tropical Medicine and Hygiene, 2005)
Diarrhea is frequent among persons infected with human immunodeficiency virus (HIV) but few interventions are available for people in Africa. We conducted a randomized controlled trial of a home-based, safe water intervention ...
Comparative studies on orphans and non-orphans in Uganda
(Center for International Health and Development, 2004-10)
There are now in Uganda more than two million orphans, i.e. children under 18 years old who have lost one or both of their parents. Roughly one in every five children is an orphan and one in every four households in the ...
Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on Antiretroviral Therapy (ART) in sub-Saharan Africa: Frequency and clinical significance
(BioMed Central, 2008-10)
Background: A proportion of individuals who start antiretroviral therapy (ART) fail to achieve adequate CD4 cell reconstitution despite sustained viral suppression. We determined the frequency and clinical significance of ...
Determination of Lamivudine, Zidovudine, and Nevirapine in capillary blood sampled on filter paper by LC
(Oxford University Press, 2009-11)
A bioanalytical method for determination of lamivudine (3TC), zidovudine (AZT), and nevirapine (NVP) in 100 μL capillary blood applied onto sampling paper has been developed and validated. The antiretroviral drugs (ARV) ...
Eligibility for HIV/AIDS treatment among adults in a medical emergency setting at an urban hospital in Uganda
(Makerere University Medical School, 2007)
Background: Despite global effort to scale up access to antiretroviral therapy (ART), many people in need of HIV/AIDS care in Uganda have not been reached. HIV testing and ART are not widely offered as routine medical ...