dc.contributor.author | Ssendikaddiwa, Emmy Bwogi | |
dc.date.accessioned | 2013-07-04T07:20:16Z | |
dc.date.available | 2013-07-04T07:20:16Z | |
dc.date.issued | 2001-06 | |
dc.identifier.uri | http://hdl.handle.net/10570/1510 | |
dc.description | A Dissertation submitted to school of postgraduate studies in partial fulfillment of the for the award of the Degree of Master of Medicine in Pathology of MAKERERE UNIVERSITY. | en_US |
dc.description.abstract | An autopsy study of the pathology of extra pulmonary tuberculosis in HIV/AIDS infection has not been carried out at Mulago Hospital before yet tuberculosis is assuming epidemic proportions in this era of HIV/AIDS and s responsible for significant mortality.
This preliminary report describes a descriptive cross-sectional autopsy study of 86 cases of adult HIV positive cadavers with extra pulmonary tuberculosis. Autopsy examinations were done, the organs sampled and tissues obtained processed for histopathology using routine H&E and ZN stains.
The results show that TB in AIDS is widely disseminated and associated with a significant mortality. The diagnosis of EPTB is difficult because the manifestations are protean and non-specific. The histological patterns are mostly a typical and characterized by areas of caseous necrosis with much nuclear debri, no surrounding epithelioid cells nor Longhan’s gaint cells, abundant AAFB’s and a scanty lymphocytic infiltrate. Most of the tuberculosis is undetected clinically. The results are discussed and compared with those obtained in studies elsewhere in the world particularly sub-Saharan Africa. | en_US |
dc.language.iso | en | en_US |
dc.subject | Pathology, | en_US |
dc.subject | Tuberculosis, | en_US |
dc.subject | HIV / AIDS, | en_US |
dc.subject | Autopsy, | en_US |
dc.subject | Mulago Hospital, | en_US |
dc.subject | Histopathology, | en_US |
dc.subject | Epithelioid cells, | en_US |
dc.subject | Sub-Saharan Africa. | en_US |
dc.title | The Pathology of Extrapulmonary Tuberculosis in HIV Positive Adults: An Autopsy study. | en_US |
dc.type | Thesis, masters | en_US |