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Effects of cytokine gene polymorphisms on il-10, tnf-α levels and oxidative stress in sickle cell disease patients from Mulago hospital, Uganda
(Makerere University, 2022-04-29)
Sickle cell disease is a major cause of death in children under 5 years in Africa. Chronic oxidative stress and the release of inflammatory cytokines contribute to sickle cell disease pathogenesis and thus complicate the ...
Seroprevalence and risk factors of Brucellosis in Camel and herdsmen in Benadir Region Somalia
(Makerere University, 2022)
Camel brucellosis is a contagious disease that is often presented in a chronic condition caused by Brucella and affects both animals and pastoralists. The disease has been partially assessed in Somalia, especially since ...
Identification of potential antigenic peptides of Bm86, Ra85A and Ra92A tick proteins using insilico tools and immune dot blot assay
(Makerere University, 2022-04-28)
Ticks are the leading causes of losses the livestock sector in sub-Saharan Africa through the spread of tick-borne infections. They are mostly controlled by chemical acaricides. The use of anti-tick vaccine to control ticks ...
Rapid detection and antibiotic resistance of Group B Streptococcus from women at Kawempe Hospital Kampala, Uganda
(Makerere University, 2022)
An accurate and rapid bedside test undertaken in labour ward to detect Group B Streptococcus (GBS) maternal colonization has the potential to improve the effectiveness of intrapartum antibiotic prophylaxis prevention ...
Congenital plasmodium falciparum infection in a meso-endemic area of Uganda : molecular perspective
(Makerere University, 2022)
Malaria remains a major public health concern especially among pregnant women and young children in sub-Saharan Africa. Few studies in Uganda have examined congenital malaria (CM) defined as presence of malaria parasites ...
Antimicrobial profiles of E. coli, Salmonella and Campylobacter spp from raw and roasted chicken meat. A case of vending points along selected highways in Uganda
(Makerere University, 2022-03)
Food-borne pathogens are an emerging threat in lieu of increased population growth and urbanization. Safety of ready-to-eat foods notably those on highways is questionable as several cases of gastro-intestinal issues have ...
Lack of association between fluconazole susceptibility and ERG11 nucleotide polymorphisms in cryptococcus neoformans clinical isolates from Uganda
(Makerere University, 2022-08)
Over 50% of Ugandan HIV-infected patients die due to cryptococcal meningitis [CM]-related complications. Fluconazole is the drug of choice for CM monoprophylaxis in resource-limited settings such as Uganda. Emerging ...
Sero-prevalence and risk factors associated with Brucella Canis infection in dogs in Zombo District, Northwestern Uganda
(Makerere University, 2022)
Canine brucellosis is an infectious debilitating disease of economic and public health significance in dogs worldwide. In Uganda, no systematic study has been conducted to establish the occurrence of the condition in dog ...
Antimicrobial resistance of staphylococcus aureus; knowledge, attitude, and practices on antibiotic use among farmers in Isingiro and Kamuli districts – Uganda
(Makerere University, 2022)
Bacterial resistance to antibiotics is fast becoming a big challenge as resistance to multiple drugs is rising rapidly. The emergence of resistant Staphylococcus aureus worldwide is life-threatening for both the human and ...
Evaluation of a sample pooling strategy for SARS-COV-2 by real time PCR
(Makerere University, 2022)
Coronavirus disease 2019 (COVID-19) started as a cluster of pneumonia cases in Wuhan, China in December 2019 and became a global pandemic of international concern. Timely laboratory diagnosis of COVID-19 of all samples ...