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Determining the functionality of the putative twin-arginine signal peptides of rhomboid proteases from Mycobacterium tuberculosis using the beta-lactamase reporter system
(Makerere University, 2020)
Rhomboid proteases are a group of integral membrane proteases present in several organisms. Because of their roles in many medically important processes, rhomboid proteases are potential drug targets. In Mycobacteria ...
The validity of novel biomarkers in improving prediction and diagnosis of coronary heart disease : a case of Mengo Hospital
(Makerere University, 2020-08-25)
Rising incidences of coronary heart disease is of great concern to public health especially among individuals without symptoms. This calls for accurate, early diagnosis which is the cornerstone for treatment, prognosis, ...
Identification of diagnostic markers for Fusarium xylarioides, the cause of coffee wilt disease in Uganda
(Makerere University, 2021-03)
Fusarium xylarioides Steyaert is the causative agent of coffee wilt disease, scientifically known as trecheomycosis. This pathogen has two races, each specific to a particular coffee species; race 1 is pathogenic to Robusta ...
Insecticide resistance and KDR mutations in malaria vector from different transmission sites in Uganda
(Makerere University, 2021-03)
Background: Despite the development of various interventions aimed at the control of the malaria vector the African Region continues to carry a disproportionately high share of the global malaria burden. This has been ...
Assessing the performance of TB-HIV activities at Masaka Regional Referral Hospital, 2012-2014
(Makerere University, 2021-02)
The TB-HIV co-infection burden globally, at regional level and locally, remains a health challenge that requires strong diagnosis, treatment and integrated support. A retrospective study was carried out at Masaka Regional ...
Effect of sputum characteristics, transportation time and HIV status on rapid detection of mycobacterium tuberculosis complex in resource limited settings
(Makerere University, 2019-06)
Globally, Tuberculosis (TB) is one of the most devastating infectious diseases and its eradication is still a challenge given the limitations of the current diagnostic technologies and capacities. Sputum characteristics ...
Bacterial pathogens associated with febrile conditions and their antimicrobial sensitivity pattern in children from Mbale hospital, Uganda
(Makerere University, 2021-02)
Bacterial pathogens constitute a significant public health problem and are important cause of morbidity and mortality in febrile patients. The study was to determine the antimicrobial sensitivity pattern of bacterial ...
Occurrence of cassava mosaic geminiviruses and cassava brown streak viruses in cassava and wild plant species in Uganda
(Makerere University, 2015)
Cassava (Manihot esculenta crantz) is an important food and cash crop worldwide. Currently cassava brown streak disease (CBSD) caused by Cassava brown streak ipomoviruses (CBSVs) and cassava mosaic disease (CMD) caused by ...
Evaluation of Bacillus thuringiensis crystal (CRY6A) and carica papaya cystatin toxins against the banana weevil (Cosmopolites sordidus) using a novel diet and construction of a plant transformation vector with two stacked toxin genes
(Makerere University, 2011-10)
The banana weevil (Cosmopolites sordidus) is a major pest of banana, plantain and Ensete. Despite the existence of control strategies that combine cultural, biological, use of botanical extracts and chemical control methods, ...
Evaluation of process procedures of selected medicinal plants used for treating malaria fevers in Tororo district
(Makerere University, 2015-03)
Background: Despite widespread utilization of medicinal plants globally, there is insufficient documentation regarding their efficacy and standard processing procedures (SPP)-leading to products with variable levels of ...