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Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial
(BioMed Central, 2009-10-24)
Background: Malaria carries high case fatality among children with sickle cell anaemia. In Uganda, chloroquine is used for prophylaxis in these children despite unacceptably high levels of resistance. Intermittent presumptive ...
Emergence of sickle cell gene through migration and intermarriage: A case study
(Africa Journal of Animal and Biomedical Sciences, 2009)
Sickle cell disease (SCD) is an inheritable disorder which is very common among persons of equatorial regions
including Africa. The evolution of SCD is linked to malaria endemicity in which sickle cell traits are selected
for ...