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    Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans 

    Mukonzo, Jackson K; Waako, Paul; Ogwal-Okeng, Jasper; Gustafsson, Lars L.; Aklillu, Eleni (Lippincott Wilkins & Williams, 2010)
    Abstract: Quinine is one of the most effective antimalarial drugs, although its clinical use is limited as a result of its narrow safety margin. Quinine is a substrate of the polymorphic p-glycoprotein and CYP3A4/3A5. This ...

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    AuthorAklillu, Eleni (1)Gustafsson, Lars L. (1)Mukonzo, Jackson K (1)Ogwal-Okeng, Jasper (1)Waako, Paul (1)Subject
    ABCB1 (1)
    CYP3A5 (1)Genetic polymorphism (1)
    Quinine (1)
    Ugandans (1)... View MoreDate Issued
    2010 (1)

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