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Factors associated with adherence to anti-tuberculosis treatment among children attending TB clinics in Mulago Hospital, Nsambya Home Care and Kawempe (KCCA Health Centre).
(Makerere University, 2014)
Introduction: Tuberculosis (TB) is a major cause of mortality and morbidity with about 8.8 million new TB cases globally in 2010.Uganda like most of Sub-Saharan Africa, has a high burden of TB and this is fuelled by the ...
Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
(Public Library of Science, 2012-06-26)
Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ...
Rifampicin for continuation phase tuberculosis treatment in Uganda: a cost-effectiveness analysis
(Public Library of Science, 2012-06)
Background: In Uganda, isoniazid plus ethambutol is used for 6 months (6HE) during the continuation treatment phase of new tuberculosis (TB) cases. However, the World Health Organization (WHO) recommends using isoniazid ...
An assessment of Makerere University College of Health Sciences: optimizing health research capacity to meet Uganda’s priorities
(BioMed Central, 2011)
Background: Health research is critical to the institutional mission of the Makerere College of Health Sciences (MakCHS). Optimizing the alignment of health research capacity at MakCHS with the health needs and priorities ...
Chest radiographic findings of pulmonary tuberculosis in severely immunocompromised patients with the human immunodeficiency virus
(The British Institute of Radiology, 2012-06)
Objective: We describe chest radiograph (CXR) findings in a population with a high
prevalence of human immunodeficiency virus (HIV) and tuberculosis (TB) in order to
identify radiological features associated with TB; to ...
Assessing the role of family support on non adherence to TB treatment by patients in Mulago hospital TB clinic
(Makerere University, 2013-08)
Background: Drug resistance among tuberculosis patients in sub-Saharan Africa is increasing mainly due to poor adherence to TB treatment despite various interventions aimed at improving treatment completion. Family support ...
Time to tuberculosis treatment default and its determinants among adult TB patients in Jinja District, A retrospective cohort study
(Makerere University, 2015-10)
Introduction: Whereas Tuberculosis is both preventable and curable, the disease remains a global health problem causing ill-health among millions of people each year and ranks as the second leading cause of death from an ...
Prevalence of chronic obstructive pulmonary disease and associated factors among HIV infected patients attending the Mulago ISS Clinic
(Makerere University, 2017-10-12)
Background: Chronic obstructive pulmonary disease (COPD) will be the 3rd leading cause of death worldwide by 2020. Data from Africa indicate that the prevalence of COPD is high (4% to 25%). We sought to determine its ...
Rhomboids of mycobacteria: insight from phylogeny, genomic and complementation analysis.
(Makerere University, 2014)
Background
The rhomboid superfamily of proteins includes novel trans-membrane Serine-proteases that occur in all life-kingdoms, and are responsible for vital roles such as signaling in Drosophila, red blood cell invasion ...