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The role of speciation in positive Lowenstein-Jensen culture isolates from a high tuberculosis burden country
(Public Library of Science, 2011-11)
Objective: To determine the need for routine speciation of positive Lowenstein-Jensen mycobacterial cultures in HIVinfected
patients suspected of having pulmonary tuberculosis at Mulago Hospital in Kampala, Uganda.
Methods: ...
Low prevalence of pneumocystis jirovecii lung colonization in Ugandan HIV-infected patients hospitalized with non-Pneumocystis pneumonia
(SciVerse ScienceDirect, 2012-02-15)
Pneumocystis jirovecii is an important opportunistic infection in human immunodeficiency virus (HIV)–infected patients. In the developed world, P. jirovecii epidemiology is marked by frequent colonization in immunosuppressed ...
Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
(Public Library of Science, 2012-06-26)
Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ...
Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV prevalence setting: a prospective cohort study
(Public Library of Science, 2011-01)
Background: Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. ...