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Early cytokine profiles associated with mild and asymptomatic COVID-19 disease severity in Uganda
(Makerere University, 2022-12-20)
Emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) constituted a global health threat of highly impactful and pandemic proportions. However, low COVID-19 disease severity was observed in Uganda ...
Genomic characterization of SARS-CoV-2 from Uganda using MinION Nanopore sequencing
(Makerere University, 2022-12)
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped virus with a single-stranded, positive-sense RNA genome of approx. 29.9 kilobase pairs. The genome undergoes genetic mutations ...
Evaluation of pre-existing cross reactive cellular immune responses to SARS-CoV-2 in Uganda
(Makerere University, 2022-12)
Background: A low severity of COVID-19 disease has been reported in the Africa population more so in Uganda as compared to other regions like Europe, America and West Pacific. Over 169,996 people have been infected with ...