Search
Now showing items 2931-2940 of 2984
Transcriptome analysis of micro-RNAs associated with COVID-19 disease
(Makerere University, 2023-11)
The host microRNA (miRNA), which is essential for maintaining the epithelial cell barrier in the
respiratory tract as well as controlling viral entry and reproduction, plays a significant role in
COVID-19 infection. ...
Health related quality of life and associated factors of post-pulmonary tuberculosis lung disease patients treated from Mulago National Referral Hospital, Kampala - Uganda
(Makerere University, 2024)
Introduction: By the end of 2020, there were approximately 155 million TB survivors globally. TB survivors have up to three times increased risk of mortality from post-Pulmonary TB lung complications compared with the ...
A machine learning approach to predict E. coli antibacterial resistance using whole-genome sequencing data
(Makerere University, 2023)
Background: Antimicrobial resistance (AMR) is a significant global health threat, particularly impacting low- and middle-income countries(LMICS) such as Uganda, where reliable and rapid methods for detecting AMR in E. coli ...
Evaluating readiness for implementation of the eight antenatal care contacts as per the World Health Organization guidelines in Bukwo District, Uganda
(Makerere University, 2023)
Background: Low and Middle Income Countries (LMICs) account for around 99 % of maternal deaths worldwide, with Sub-Saharan Africa (SSA) responsible for about 66 % of these demises. The new Antenatal Care (ANC) model with ...
Uptake of preventive nutrition interventions among caretakers of children under 5 years in a pastoral setting of South Sudan: A case of Kapoeta South County
(Makerere University, 2023)
Background: Preventive nutrition interventions are usually implemented without understanding how multiple factors affect uptake. Pastoralist populations have shown low uptake. A multidimensional study of uptake in the ...
Effect of perioperative blood transfusion on complications following emergency non-trauma laparotomy: A prospective cohort study
(Makerere University, 2024)
Introduction: Blood transfusion may be required in the management of patients undergoing emergency non-trauma laparotomy. However, retrospective cohort studies involving patients undergoing emergency laparotomy have ...
Factors associated with virological non-suppression among adult HIV clients with low-level viremia in Kampala, Uganda
(Makerere University, 2022)
The goal of antiretroviral therapy is to maximize the inhibition of infectious virion production to below the level of detection of less than 50 copies/ml. Clients with LLV have not been fully studied in Uganda and ...
Costs of tuberculosis care and associated factors among patients with HIV or diabetes mellitus comorbidities attending selected health facilities in Kampala from a societal perspective
(Makerere University, 2023)
Introduction
In Uganda, the Tuberculosis (TB) burden among Human immunodeficiency virus (HIV) patients is still high and increasing significantly among DM patients due to the looming DM epidemic. Although TB drugs and ...
Detection of mycobacterium tuberculosis complex DNA in CD34 positive versus CD34-Negative peripheral blood mononuclear cells and the determinants of IGRA positivity in latent Tuberculosis
(Makerere University, 2023)
Background
Tuberculin skin test (TST) and interferon gamma release assay (IGRA), currently used to diagnose latent
tuberculosis infection (LTBI) have low positive predictive values for progression to active tuberculosis ...
Access to improved sanitation among households in peri urban area in Bwaise II Parish, Kawempe Division: A cross sectional study
(Makerere University, 2023)
Introduction: Sustainable Development Goal (SDG) target 6.2 aims at achieving universal access to sanitation, leaving no one behind by 2030. To enhance this achievement, SDG target 1.4 aims at basic sanitation for all ...