Browsing College of Health Sciences (CHS) by Author "Talisuna, Ambrose"
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Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda
Yeka, Adoke; Kamya, Moses R.; Dorsey, Grant; Talisuna, Ambrose; Lugemwa, Myers; Rwakimari, John Bosco; Staedke, Sarah G.; Rosenthal, Philip J.; Wabwire-Mangen, Fred; Bukirwa, Hasifa (Public Library of Science, 2008-06)Background: Uganda recently adopted artemether-lumefantrine (AL) as the recommended first-line treatment for uncomplicated malaria. However, AL has several limitations, including a twice-daily dosing regimen, recommendation ... -
Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria in Uganda
Bukirwa, Hasifa; Talisuna, Ambrose; Yeka, Adoke; Kamya, Moses R; Talisuna, Ambrose O.; Banek, Kristin; Bakyaita, Nathan; Rwakimari, John Bosco; Rosenthal, Philip J.; Wabwire-Mangen, Fred; Dorsey, Grant; Staedke, Sarah G. (Public Library of Science, 2006-05)Objectives: To compare the efficacy and safety of artemisinin combination therapies for the treatment of uncomplicated falciparum malaria in Uganda. Design: Randomized single-blind controlled trial. Setting: Tororo, Uganda, ... -
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda
Banek, Kristin; Yeka, Adoke; Bakyaita, Nathan; Staedke, Sarah G.; Talisuna, Ambrose; Kironde, Fred; Kamya, Moses.R; Nsobya, Samuel L.; Kilian, Albert; Slater, Madeline; Dorsey, Grant; Wabwire-Mangen, Fred; Rosenthal, Philip J.; Reingold, Arthur (Public Library of Science, 2005-07)Background Drug resistance in Plasmodium falciparum poses a major threat to malaria control. Combination antimalarial therapy including artemisinins has been advocated recently to improve efficacy and limit the spread of ... -
Complexity of plasmodium falciparum infections and antimalarial drug efficacy at 7 sites in Uganda.
Sulggi, Less A.; Nsobya, Samuel L.; Yeka, Adoke; Dokomajilar, Christian; Rosenthal, Philip J.; Talisuna, Ambrose; Dorsey, Grant (University of Chicago Press, 2006-03-13)Malaria infections in Africa frequently include multiple parasite strains.We examined the relationship between the number of infecting Plasmodium falciparum strains and the responses to 3 different combination therapies ... -
Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda
Bakyaita, Nathan; Dorsey, Grant; Adoke, Yeka; Banek, Kristin; Staedke, Sarah G.; Kamya, Moses R.; Talisuna, Ambrose; Kironde, Fred; Nsobya, Sam; Kilian, Albert; Reingold, Arthur; Rosenthal, Philip J.; Wabwire-Mangen, Fred (2005)The use of combinations of inexpensive drugs for the treatment of malaria in Africa has been proposed as an interim policy while awaiting the widespread availability of more effective regimens. We compared sulfadoxinepyrimethamine ...