Browsing College of Health Sciences (CHS) by Subject "Malaria"
Now showing items 1-20 of 118
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Access to health care for febrile children in Uganda: symptom recognition, care seeking practices and provider choice
(Karolinska Institutet and Makerere University, 2009)Background: Febrile illnesses including malaria and pneumonia are leading causes of death among children under five in Uganda. Despite government efforts to increase health care access by offering free services at government ... -
Adherence to malaria management guidelines by health care workers in the Busoga Sub-region, Eastern Uganda
(BMC, 2022)Background: Appropriate malaria management is a key malaria control strategy. The objective of this study was to determine health care worker adherence levels to malaria case management guidelines in the Busoga sub-region, ... -
The age-specific incidence of hospitalized paediatric malaria in Uganda
(BMC, 2020)Background: Understanding the relationship between malaria infection risk and disease outcomes represents a fundamental component of morbidity and mortality burden estimations. Contemporary data on severe malaria risks ... -
Antimalarial drug levels in biological samples: methods and applications.
(2008-09)This thesis deals with the development and validation of analytical methods that are field-adapted and their application in the determination of antimalarial drug levels in biological samples. These methods are suitable ... -
Artemether-Lumefantrine combination therapy for treatment of uncomplicated malaria: The potential for complex interactions with antiretroviral drugs in HIV-infected individuals
(Malaria Research and Treatment, 2011-02-14)Treatment of malaria in HIV-infected individuals receiving antiretroviral therapy (ART) poses significant challenges. Artemether-lumefantrine (AL) is one of the artemisisnin-based combination therapies recommended for ... -
Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda
(Public Library of Science, 2008-06)Background: Uganda recently adopted artemether-lumefantrine (AL) as the recommended first-line treatment for uncomplicated malaria. However, AL has several limitations, including a twice-daily dosing regimen, recommendation ... -
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial.
(2007-05-18)Objectives: To compare the efficacy and safety of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) for treating uncomplicated falciparum malaria in Uganda. Design: Randomized single-blinded clinical ... -
Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria in Uganda
(Public Library of Science, 2006-05)Objectives: To compare the efficacy and safety of artemisinin combination therapies for the treatment of uncomplicated falciparum malaria in Uganda. Design: Randomized single-blind controlled trial. Setting: Tororo, Uganda, ... -
Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria (Review)
(Cochrane Collaboration, 2010)Background Multiple-drug-resistant malaria is widespread, and in South-East Asia resistance is high against nearly all single therapy antimalarial drugs. Here, and in other areas with low malaria transmission, the combination ... -
Assessment of availability of antimalarials and providers’ knowledge on malaria and antimalarials in private pharmaceutical outlets of Bushenyi District
(Makerere University, 2010-07)Introduction: Malaria is the leading cause of morbidity and mortality and the cause of significant economic losses in Uganda and Bushenyi District. As a response to increasing levels of antimalarial resistance National ... -
An assessment of Makerere University College of Health Sciences: optimizing health research capacity to meet Uganda’s priorities
(BioMed Central, 2011)Background: Health research is critical to the institutional mission of the Makerere College of Health Sciences (MakCHS). Optimizing the alignment of health research capacity at MakCHS with the health needs and priorities ... -
Assessment of the process of implementation of intermittent preventive treatment of malaria in pregnancy strategy in Tororo District, Uganda.
(2009)INTRODUCTION: Malaria in pregnancy is a long known problem in Uganda associated with maternal and child morbidity, mortality and disability. In Uganda, the MOH malaria control strategy mainly focuses on IPT, early diagnosis ... -
Association between indoor residual spraying and pregnancy outcomes: a quasi-experimental study from Uganda
(Oxford University Press, 2022)Background: Malaria is a risk factor for adverse pregnancy outcomes. Indoor residual spraying with insecticide (IRS) reduces malaria infections, yet the effects of IRS on pregnancy outcomes are not well established. We ... -
Associations between aminoquinoline resistance genotypes and clinical presentations of Pplasmodium falciparum Infection in Uganda
(American Society for Microbiology., 2020)Mutations that mediate resistance of Plasmodium falciparum to aminoquinoline antimalarials are selected by prior drug use and may alter parasite fitness, but associations with clinical presentations are uncertain. We ... -
Availability of child-friendly medicines and child caretaker knowledge on administering them among children below 5 years at lower public health facilities under Kampala Capital City Authority
(Makerere University, 2014-11)Introduction In 2011, an estimated 7.6 million children under the age of 5 years died globally (Lozano et al.,2011). In Uganda, 32% of childhood mortality is due to malaria (MoH, 2010) and another 17–26% attributed to ... -
Campylobacter spp among Children with acute diarrhea attending Mulago hospital in Kampala - Uganda
(2002-05)Introduction HIV positive (HIV+) women are more susceptible to malaria infection during pregnancy than their HIV negative (HIV-) counterparts but the actual prevalence of infection in Ugandan pregnant women is not known. ... -
Can community health workers and caretakers recognise pneumonia in children? Experiences from Western Uganda
(Elsevier, 2006)Acute respiratory infections (ARI) are leading killers of children. Case management using community health workers (CHW) has halved ARI mortality in children in Asia. WHO/UNICEF recommend integrating pneumonia into Home ... -
Chlorproguanil-dapsone for treating uncomplicated malaria (Review)
(JohnWiley & Sons, 2010)Background In Africa, malaria is often resistant to chloroquine and sulfadoxine-pyrimethamine. Chlorproguanil-dapsone is a potential alternative. Objectives To compare chlorproguanil-dapsone with other antimalarial drugs ... -
Cognition, behaviour and academic skills after cognitive rehabilitation in Ugandan children surviving severe malaria: a randomised trial
(BioMed Central, 2011)Background: Infection with severe malaria in African children is associated with not only a high mortality but also a high risk of cognitive deficits. There is evidence that interventions done a few years after the illness ... -
Community effectiveness of malaria treatment in Uganda: a long way to Abuja targets
(Taylor & Francis, 2005)Introduction: At the Roll Back Malaria summit for African countries in Abuja, the heads of state committed to ensure that by the year 2005 at least 60% of those suffering from malaria would have access to effective treatment ...