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Comparison of Widal's test and bacterial culture as diagnostic tests for typhoid fever in humans and investigation of antimicrobial resistance of salmonella typhi isolates from patients attending private health facilities in Mbale City, Uganda
(Makerere University, 2021-02)
Due to lack of microbiology facilities, private health facilities in Mbale City are still depending on the Widal’s test that is no longer recommended to diagnose typhoid fever, a disease that is responsible for about 200,000 ...
Differentiation patterns of Trypanosoma Brucei field isolates
(Makerere University, 2021-03)
The developmental biology of differentiation is a universal biological process that allows cells to adapt to different environments and to perform specific functions. In the life cycle of T. brucei, this process is tightly ...
Prevalence of helicobacter pylori cytotoxic-associated genes and its association with treatment outcomes amongst dyspeptic patients in South Western Uganda
(Makerere University, 2021-02)
Helicobacter pylori (H. pylori) is a gram-negative fastidious bacteria that infect the stomach. H. pylori virulent strains is associated with severe gastritis, ulcerative disease and the upper gastrointestinal malignancies. ...
Optimization and evaluation of loop-mediated isothermal amplification (LAMP) system for detection of Pseudocercospora angolensis in citrus cinensis
(Makerere University, 2021-03)
Pseudocercospora angolensis causes Pseudocercospora leaf and fruit spot disease in citrus which can result in up to 100% yield loss. Early diagnosis of this disease is vital for effective control. This study aimed at ...
Antibacterial activity and acute toxicity of herbs used in treatment of water borne diarrheal diseases in Butaleja District
(Makerere University, 2021-04)
Uganda is still negatively impacted by a huge burden of water borne diseases, the heaviest being diarrhoeal diseases. This may result in high morbidity and mortality rates if left unattended to. The study documented herbs ...
Determining the functionality of the putative twin-arginine signal peptides of rhomboid proteases from Mycobacterium tuberculosis using the beta-lactamase reporter system
(Makerere University, 2020)
Rhomboid proteases are a group of integral membrane proteases present in several organisms. Because of their roles in many medically important processes, rhomboid proteases are potential drug targets. In Mycobacteria ...
The validity of novel biomarkers in improving prediction and diagnosis of coronary heart disease : a case of Mengo Hospital
(Makerere University, 2020-08-25)
Rising incidences of coronary heart disease is of great concern to public health especially among individuals without symptoms. This calls for accurate, early diagnosis which is the cornerstone for treatment, prognosis, ...
Identification of diagnostic markers for Fusarium xylarioides, the cause of coffee wilt disease in Uganda
(Makerere University, 2021-03)
Fusarium xylarioides Steyaert is the causative agent of coffee wilt disease, scientifically known as trecheomycosis. This pathogen has two races, each specific to a particular coffee species; race 1 is pathogenic to Robusta ...
Insecticide resistance and KDR mutations in malaria vector from different transmission sites in Uganda
(Makerere University, 2021-03)
Background: Despite the development of various interventions aimed at the control of the malaria vector the African Region continues to carry a disproportionately high share of the global malaria burden. This has been ...
Assessing the performance of TB-HIV activities at Masaka Regional Referral Hospital, 2012-2014
(Makerere University, 2021-02)
The TB-HIV co-infection burden globally, at regional level and locally, remains a health challenge that requires strong diagnosis, treatment and integrated support. A retrospective study was carried out at Masaka Regional ...