Browsing by Author "Kityo, Cissy"
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Effect of food on the steady-state pharmacokinetics of tenofovir and emtricitabine plus efavirenz in Ugandan adults
Lamorde, Mohammed; Byakika-Kibwika, Pauline; Tamale, William S.; Kiweewa, Francis; Ryan, Mairin; Amara, Alieu; Tjia, John; Back, David; Khoo, Saye; Boffito, Marta; Kityo, Cissy; Merry, Concepta (Hindawi Publishing Corporation, 2012-02-20)We investigated the effect of food on the steady-state pharmacokinetics of a proprietary fixed-dose combination (FDC) tablet containing tenofovir disoproxil fumarate (TDF)/emtricitabine/efavirenz. Fifteen Ugandan HIV-1 ... -
Efficacy and safety of dolutegravir or darunavir in combination with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection (NADIA): week 96 results from a prospective, multicentre, open-label, factorial, randomised, non-inferiority trial
Paton, Nichilas I.; Musaazi, Joseph; Kityo, Cissy; Walimbwa, Stephen; Hoppe, Anne; Balyegisawa, Apolo; Asienzo, Jesca; Kaimal, Arvind; Mirembe, Grace; Lugemwa, Abbas; Ategeka, Gilbert; Borok, Margaret; Mugerwa, Henry; Siika, Abraham; Odongpiny, Eva Laker A.; Castelnuovo, Barbara; Kiragga, Agnes; Kambugu, Andrew (Elsevier, 2022-04-20)Background WHO guidelines recommend dolutegravir plus two nucleoside reverse transcriptase inhibitors (NRTIs) for second-line HIV therapy, with NRTI switching from first-line tenofovir to zidovudine. We aimed to ... -
Prevalence, incidence and predictors of severe anaemia with zidovudine-containing regimens in African adults with HIV infection within the DART trial
Ssali, Francis; Stöhr, Wolfgang; Munderi, Paula; Reid, Andrew; Walker, A Sarah; Gibb, Diana M.; Mugyenyi, Peter; Kityo, Cissy; Grosskurth, Heiner; Hakim, James; Byakwaga, Helen; Katabira, Elly; Darbyshire, Janet H.; Gilks, Charles F. (International Medical Press, 2006)Objective: To describe the prevalence, incidence and predictors of severe anaemia in previously untreated symptomatic HIV-infected adults with CD4+ T-cells <200 cells/mm3 initiating zidovudine-containing regimens in Africa. ... -
Severe Renal Dysfunction and Risk Factors Associated with Renal Impairment in HIV-Infected Adults in Africa Initiating Antiretroviral Therapy
Reid, Andrew; Stohr, Wolfgang; Walker, Sarah A; Williams, Ian G.; Kityo, Cissy; Hughes, Peter; Kambugu, Andrew; Gilks, Charles F.; Mugyenyi, Peter; Munderi, Paula; Hakim, James; Gibb, Diana M. (CID, 2008)Background. We sought to investigate renal function in previously untreated symptomatic human immunodeficiency virus (HIV)–infected adults with CD4+ cell counts of !200 cells/mm3 who were undergoing antiretroviral therapy ... -
Treatment interruptions predict resistance in HIV-positive individuals purchasing fixed-dose combination antiretroviral therapy in Kampala, Uganda
Oyugi, Jessica H.; Byakika-Tusiime, Jayne; Ragland, Kathleen; Laeyendecker, Oliver; Mugerwa, Roy; Kityo, Cissy; Mugyenyi, Peter; Quinn, Thomas C.; Bangsberg, David R. (Lippincott, Williams & Wilkins, 2007)Objective: To evaluate adherence, treatment interruptions, and outcomes in patients purchasing antiretroviral fixed-dose combination (FDC) therapy. Design: Ninety-seven participants were recruited into a prospective 24-week ...