Browsing by Subject "Cytokines"
Now showing items 1-4 of 4
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Biomarkers of HIV immune reconstitution inflammatory syndrome
(Future Medicine, 2008)Dysregulation of the immune system drives HIV pathogenesis. As we develop new ways to treat HIV and AIDS, we encounter new clinical ramifications of our treatment on regulatory components of the Immune system. HIV-associated ... -
Ethnopharmacology, cytotoxicity, antiviral and immunomodulatory profiles of medicinal plant species used by herbalists in treating people living with HIV/AIDS in Uganda
(Makerere University, 2021-11-07)Opportunistic infections (OI) are the single most important cause of mortality and morbidity among PLHIV in poor countries. There is widespread use of medicinal plants among PLHIV. However, there is no scientific information ... -
Mycobacterium tuberculosis associated immune activation, inhibition and exhaustion profiling to predict active tuberculosis disease among presumptive tuberculosis participants and monitor anti-tuberculosis treatment response.
(Makerere University, 2023)Globally, tuberculosis (TB) is the leading cause of mortality and morbidity especially among resource-limited populations including Uganda. This statistic is greatly fueled by the delay in diagnosis of the disease and ... -
Prediction of immune state and viral suppression in HIV-1 infection using IL-6: IFN-γ ratios
(Makerere University, 2023-03-06)Introduction: Cytokine dysregulation is a hallmark of HIV infection with a rise in plasma IL-6 largely reported to enhance HIV-1 replication while IFN-γ shows hindrance. Besides, IL-6 inhibits IFN-γ secretion through the ...