Browsing by Subject "Breast cancer"
Now showing items 1-20 of 20
-
Assessment of patient delay among women presenting with breast cancer at Mulago Hospital: Magnitude and factors.
(Makerere University, 2014)Background: In Uganda, the majority of patients with breast cancer present with advanced disease which is majorly attributed to late presentation and this is associated with low survival rates. The aim of this study was ... -
Association between RBC folate levels with breast cancer in patients seen at Mulago National Referral Hospital: A case-control study.
(Makerere University, 2012)Background: Folate has been shown to play a complex but unclear role in carcinogenesis, with, some studies showing that low folate intake protects against early while high folate intake promoting advanced carcinogenesis. ... -
Awareness of breast cancer risk factors and early detection measures and associated factors among nurses and midwives at Mulago Hospital
(Makerere University, 2009-05)Background: Breast cancer is the most common malignancy affecting women, and second cause of cancer death in the world, with more than one million cases occurring worldwide annually. The chance of a woman having invasive ... -
BRCA1 and BRCA2 mutations in selected exons in breast cancer patients attending Mulago Hospital, Uganda
(Makerere University, 2017-02)Breast cancer 1 (BRCA1) and Breast cancer 2 (BRCA2), mutation recognition is crucial for cancer risk assessment, identification of suitable breast cancer treatments, and personalised breast cancer prophylaxis in mutation ... -
Breast cancer guidelines for Uganda (2nd Edition 2007)
(Makerere University Medical School, 2008-06)Breast cancer in Uganda is the third commonest cancer in women coming only next to cancer of the cervix and Kaposi’s sarcoma. The incidence of breast cancer in Uganda has doubled from11: 100,000 in 1961 to 22:100,000 in ... -
Breast cancer knowledge, practice of preventive measures and associated factors among rural women aged 20 – 49 years in Kigulu County, Iganga District
(Makerere University, 2017)Background: In Uganda 1,100 women die of breast cancer every year, with a patient peak age of 30 -39 years, majority of patients present late at stage III and IV. Early detection remains a major effective approach to combat ... -
Breast Cancer Molecular Subtype Prevalence and Commonly Mutated Genes in Triple Negative Breast Cancer in Uganda
(Makerere University, 2022-11-25)Breast cancer is the second commonest cancer in women in Uganda, accounting for about 21% of all cancer related mortality in women in Uganda. An estimated 35-36% of all breast cancer patients in Uganda have triple negative ... -
c-erb-2 oncoprotein over-expression in breast cancer and its relationships to histology type and grade in a Uganda population
(East African Medical Journal, 2006-08)Objective: To evaluate c-erbB-2 oncoprotein over expression in breast cancer patients of Kyadondo county and also relate this oncoprotein to histological type and grade of the tumour. Design: Cross-sectional study. Setting: ... -
Developing a prediction model to detect the likelihood of early-stage breast cancer using machine learning techniques at the Uganda Cancer Institute
(Makerere University, 2021-06-02)Background: Breast cancer is the most common malignancy affecting women worldwide, with over one million cases occurring annually. It is the second most common cause of cancer-related death in the world. In Uganda, it is ... -
Insulin-like growth factor-I as a risk factor for breast cancer among Ugandan women in Mulago National Referral Hospital
(Makerere University, 2012-06)Background: In Uganda breast cancer is the third commonest cancer in women after cancer of the cervix and Kaposi's sarcoma. The incidence of breast cancer in Uganda has nearly tripled from 11:100,000 in 1961 to 31:100,000 ... -
Knowledge, attitudes and practices of breast cancer screening among rural women in Bubaare Sub-County, Rubanda District
(Makerere University, 2018-08-30)Introduction: Breast cancer in women is a major public health burden and the most common cancer among women Worldwide. Though its incidence is greater in high income countries, in sharp contrast, mortality rates are greatest ... -
Late age at first child birth as a risk factor of breast cancer among Ugandan women at Mulago Hospital: A case control study.
(2012-05)Background Breast Cancer in Uganda is the third commonest cancer in women after cancer of the cervix and Kaposis sarcoma. The incidence of Breast Cancer in Uganda has nearly tripled from 11:100,000 in 1961 to 31:100,000 ... -
The National Diagnostic Reference Levels for digital diagnostic and screening mammography in Uganda
(Makerere University, 2023)Introduction: Mammography is the most effective screening modality for breast cancer due to the early detection of breast lesions. Breast tissue is highly sensitive to radiation. The risk of radiation-induced breast cancer ... -
Non-BRCA breast cancer predisposing variants identified in Kenyan patients using whole-exome sequencing
(Makerere University, 2022-07)Background: Breast cancer is a leading cause of cancer-related mortality in women worldwide. This disease is reported to be associated with mutations in several predisposing genes in addition to the long known BRCA1/2. ... -
The prevalence and clinico-pathological features of benign proliferative breast diseases among female patients at Mulago Hospital: across-sectional study
(Makerere University, 2013-06)Background: Although the increasing incidence of breast cancer in Uganda has been well-documented, the possibility that benign proliferative breast disease (BPBD) among Ugandan women is increasing has not been determined. ... -
The prevalence of palpable breast lumps among young women attending Makerere University and their awareness of breast self examination
(2009)Introduction: The commonest presenting symptom among women attending the breast clinic in Mulago Hospital is a lump. Whereas breast lumps form the biggest burden of disease in Mulago hospital breast clinic and breast lump ... -
Prevalence of triple negative breast cancer and its associated clinico-histopathological characteristics among women with primary breast cancer at Mulago hospital.
(Makerere University, 2012)Background Globally, breast cancer is the most frequently diagnosed life threatening cancer and leading cause of cancer death among women. In Uganda, breast cancer is the third most commonly diagnosed cancer after Kaposi’s ... -
Sonographic findings in women with mammographically dense breast tissue at Mulago Hospital.
(Makerere University, 2014)Back ground The incidence rate of breast cancer in sub-Saharan nations is increasing. In Uganda, the incidence of breast cancer has tripled in the past three decades. Mammography, the gold standard for breast cancer ... -
Using Gene and miRNA expression profiles in Breast cancer risk prediction : a machine learning-based approach
(Makerere University, 2022)Breast cancer (BC) incidence is commonly accompanied by poor treatment outcomes due to late diagnosis. BC risk prediction is important for timely diagnosis but it’s clinical utility is limited by high risk bias. Genetic ... -
Willingness to screen for breast cancer among adult females attending Mulago National Referal Hospital
(Makerere University, 2016-11)Background Breast cancer incidence has increased worldwide, with exceptionally high mortality in Sub-Saharan African women, mostly due to late disease diagnosis. Breast cancer screening is crucial to identifying cancer ...