Browsing by Author "Laeyendecker, Oliver"
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HIV Subtype D Is Associated with Dementia, Compared with Subtype A, in Immunosuppressed Individuals at Risk of Cognitive Impairment in Kampala, Uganda
Sacktor, Ned; Nakasujja, Noeline; Skolasky, Richard L.; Rezapour, Mona; Robertson, Kevin; Musisi, Seggane; Katabira, Elly; Ronald, Allan; Clifford, David B.; Laeyendecker, Oliver; Quinn, Thomas C. (Clinical Infectious Diseases, 2009)Background. In the United States, clade B is the predominant human immunodeficiency virus (HIV) subtype, whereas in sub-Saharan Africa, clades A, C, and D are the predominant subtypes. HIV subtype may have an impact on ... -
Spatial phylodynamics of HIV-1 epidemic emergence in East Africa.
Serwadda, David; Gray, Rebecca R.; Tatem, Andrew J.; Lamers, Susanna; Hou, Wei; Laeyendecker, Oliver; Sewankambo, Nelson; Gray, Ronald H.; Wawer, Maria J.; Quinn, Thomas C.; Goodenow, Maureen M.; Salemi, Marco (2009-09-11)Design—We sought to investigate the evolutionary and historical reasons for the different epidemiological patterns of HIV-1 in the early epidemic. In order to characterize the demographic history of HIV-1 subtypes A and D ... -
Treatment interruptions predict resistance in HIV-positive individuals purchasing fixed-dose combination antiretroviral therapy in Kampala, Uganda
Oyugi, Jessica H.; Byakika-Tusiime, Jayne; Ragland, Kathleen; Laeyendecker, Oliver; Mugerwa, Roy; Kityo, Cissy; Mugyenyi, Peter; Quinn, Thomas C.; Bangsberg, David R. (Lippincott, Williams & Wilkins, 2007)Objective: To evaluate adherence, treatment interruptions, and outcomes in patients purchasing antiretroviral fixed-dose combination (FDC) therapy. Design: Ninety-seven participants were recruited into a prospective 24-week ...