Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?
Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?
Date
2009-03
Authors
Shihab, Hasan M
Lutwama, Fred
Piloya, Theresa
Castelnuovo, Barbara
Kambugu, Andrew D.
Colebunders, Robert
Journal Title
Journal ISSN
Volume Title
Publisher
Open Learning on Enteric Pathogens
Abstract
A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient attending an HIV treatment centre in Kampala, Uganda, who presented with bilateral non-tender pitting inflammatory edema two weeks after switching to a Lopinavir/Ritonavir-containing second-line treatment regimen. The lack of an alternate explanation led us to suspect that Lopinavir/Ritonavir was potentially responsible for the edema
Description
Case report
Keywords
Edema,
Lopinavir/Ritonavir,
Resource-limited settings,
HIV/AIDS,
Uganda,
Antiretroviral therapy
Citation
Shihab, H.M., Lutwama, F., Piloya, T., Castelnuovo, B., Kambugu, A.D., Colebunders, R. (2009). Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause? Journal of Infection in Developing Countries, 3(5)