Makerere University Institutional Repository: Recent submissions
Now showing items 1-20 of 14175
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The Clinical Presentation and Factors Associatedwith Disease Severity of Rheumatoid Arthritis inUganda: A Cross-Sectional Study
(2022)Background Rheumatoid arthritis (RA) is a chronic, debilitating disease that leads to joint destruction and disability if left untreated. Few studies on RA have been conducted in Uganda, and there is limited information ... -
Prevalence of arps10, fd, pfmdr-2, pfcrt and pfkelch13 gene mutations in Plasmodium falciparum parasite population in Uganda
(PloS ONE, 2022)In Uganda, Artemether-Lumefantrine and Artesunate are recommended for uncomplicated and severe malaria respectively, but are currently threatened by parasite resistance. Genetic and epigenetic factors play a role in ... -
Restructuring and the performance of public enterprises in Uganda : a case study of Uganda Posts & Telecommunications Corporation, 1996 - 2000
(Makerere University, 2001)The objectives of this study were to establish the objectives for restructuring the UPTC, evaluate the restructuring process, assess the performance of UTL after restructuring, examine the persisting problems and suggest ... -
A case study of the impact of project management on the construction of Kiyombya Seed Secondary School, Kiyombya Subcounty, Bunyangabu District
(Makerere University, 2020)This study offers a brief review the construction methodology and aspects of construction project management practice exercised by the author while part of the Procurement and supervision of the contractor and consequently ... -
Sustainable construction in Uganda - case study : construction of UNICEF-WFP common premises offices in Mbuya, Kampala
(Makerere University, 2024)This report documents a case study of sustainable construction in Uganda. This is the “Construction of UNICEF-WFP Common Premises Offices in Mbuya”. My role as the Quantity Surveyor at the initial stages of the project ... -
Identification of pathogen genomic differences that impact human immune response and disease during cryptococcus neoformans infection
(American Society for Microbiology, 2019)Patient outcomes during infection are due to a complex interplay between the quality of medical care, host immunity factors, and the infecting pathogen’s characteristics. To probe the influence of pathogen genotype on human ... -
Assessment of parasite clearance following treatment of severe malaria with intravenous artesunate in Ugandan children enrolled in a randomized controlled clinical trial
(BMC, 2018)Background Malaria control largely depends on availability of highly efficacious drugs, however, over the years, has been threatened by emergence of drug resistance. It is, therefore, important to monitor the impact of ... -
Contrasting impact of rural, versus urban, living on glucose metabolism and blood pressure in Uganda
(Wellcome Open research, 2020)Background: The burden of cardiometabolic diseases, including cardiovascular diseases and diabetes, is increasing in sub-Saharan Africa and this has been linked to urbanisation. Helminths, through their immunomodulatory ... -
Defining gaps in pre-exposure prophylaxis delivery for pregnant and post-partum women in high-burden settings using an implementation science framework
(Elsevier, 2020)Pregnancy is a high-risk period for HIV acquisition in African women, and pregnant women who become acutely infected with HIV account for up to a third of vertical HIV transmission cases in African settings. To protect ... -
Sustained positive impact on tuberculosis treatment outcomes of TB-HIV integrated care in Uganda
(The Union, 2019)OBJECTIVE: To examine tuberculosis (TB) treatment outcomes from a long-term TB-HIV (human immunodeficiency virus) integrated model of care at the Infectious Diseases Institute Clinic, Kampala, Uganda. METHODS: We included ... -
Risk factors associated with cervical cancer diagnosis among women living with HIV: a modified poisson regression analysis
(Makerere University, 2025)Cervical cancer is a leading cancer among women, with approximately 570,000 new cases and 311,000 deaths annually. Women living with HIV face a sixfold higher risk of developing cervical cancer than those without HIV. ... -
Performance of lipoarabinomannan assay using cerebrospinal fluid for the diagnosis of tuberculous meningitis among HIV patients
(Wellcome Open Research, 2019)Background: The diagnostic utility of the Mycobacteria tuberculosis lipoarabinomannan (TB-LAM) antigen lateral flow assay on cerebrospinal fluid (CSF) for the diagnosis of tuberculous meningitis (TBM) has not been extensively ... -
A public health approach to cervical cancer screening in Africa through community-based self-administered HPV testing and mobile treatment provision
(Wiley, 2020)The World Health Organization (WHO) refers to cervical cancer as a public health problem, and sub-Saharan Africa bears the world's highest incidence. In the realm of screening, simplified WHO recommendations for low-resource ... -
Castelnuovo, B. et al. (2018). Antiretroviral treatment Long-Term (ALT) cohort: a prospective cohort of 10 years of ART-experienced patients in Uganda
(BMJ, 2018)Purpose Little information is available on patients on antiretroviral treatment (ART) after a long-term period from sub-Saharan Africa, with the longest follow-up and related outcomes being after 10 years on ART. At the ... -
The impact of early childhood experiences of abuse and working conditions on psychological wellbeing of domestic workers in Kampala City, Uganda
(Makerere University, 2024)The recent global increase in mental health challenges exhibited by domestic workers at work place prompted many scholars in social and behavioral sciences to conduct research aimed to understand drivers of this phenomenon. ... -
A Prospective Evaluation of a multisite Cryptococcal Screening and Treatment program in HIV clinics in Uganda
(Lippincott, 2018)Background—Cryptococcus is a leading cause of AIDS-related mortality. Cryptococcal antigen (CrAg) is detectable in blood before meningitis onset, and predicts death. CrAg screening amongst those with advanced HIV, and ... -
Adolescent pregnancy at antiretroviral therapy (ART) initiation: a critical barrier to retention on ART
(Wiley Online Library, 2018)Introduction: Adolescence and pregnancy are potential risk factors for loss to follow-up (LTFU) while on antiretroviral therapy (ART). We compared adolescent and adult LTFU after ART initiation to quantify the impact of ... -
Issues with measuring hepatitis prevalence in resource-limited settings
(Elsevier, 2018) -
Molecular tests expedite the diagnosis of multidrug-resistant tuberculosis in childhood
(Academia.edu, 2018)The diagnosis of paediatric tuberculosis (TB) is difficult, partly due to the low accuracy of traditional tests. Molecular TB tests can diagnose presumptive TB and drug-resistant TB (DR-TB) rapidly and may guide crucial ... -
Risk factors for and types of oesophageal cancer
(The Lancet, 2004)