College of Veterinary Medicine, Animal Resources and BioSecurity (CoVAB): Recent submissions
Now showing items 101-120 of 292
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Genotypes of Hepatitis B Virus in Sera of patients positive for HbsAg at Jinja Regional Referral Hospital between January-April, 2019
(Makerere University, 2022)Hepatitis B virus infection is a serious disease that manifests clinically either as an acute hepatitis or in various chronic conditions causing approximately 650,000 deaths worldwide every year. About 10% of the Uganda’s ... -
Sero prevalence and Brucella species circulating among small ruminants and their attendants in Kasese and Rubirizi Districts, South-Western Uganda
(Makerere University, 2022-09-05)In Uganda, brucellosis is more widely studied in cattle than in other species of animals. A few studies conducted on Brucellosis in small ruminants suggest that there exists a significant association between caprine, ovine ... -
Bovine mastitis on selected farms in Kamwenge District: prevalence and antibiograms of the causative bacteria
(Makerere university, 2022-10-10)Bovine mastitis is an inflammation of the parenchyma of mammary glands characterized by physical, chemical, and usually bacteriological changes in milk, and pathological changes in glandular tissues of the udder. It is a ... -
Inflammatory marker profiles and seizure control in children with Nodding syndrome on antiepileptic drug therapy
(Makerere University, 2018-09)Background Nodding syndrome (NS) is a neurological disorder afflicting patients in Africa. The disease progresses from a prodromal stage to head nodding (its distinctive feature). Thereafter, convulsive seizures, worsening ... -
Lack of association between fluconazole susceptibility and ERG11 nucleotide polymorphisms in cryptococcus neoformans clinical isolates from Uganda
(Makerere University, 2022-08)Over 50% of Ugandan HIV-infected patients die due to cryptococcal meningitis [CM]-related complications. Fluconazole is the drug of choice for CM monoprophylaxis in resource-limited settings such as Uganda. Emerging ... -
Evaluation of nanoparticles and phages as candidate therapeutic agents for carbapenem resistant Klebsiella pneumoniae and Escherichia coli
(Makerere University, 2022-09)Centred on the current rate of antibiotics production and approvals, it is anticipated that by 2050 up to 10 million people could die annually due to multidrug-resistant (MDR) pathogens. One of the notable examples of ... -
Free-roaming domestic dog ecology: Population size and management in Soroti City
(Makerere University, 2022-08)Free-roaming dogs pose a public health threat. They are involved in the transmission of diseases to humans, livestock and wildlife. These dogs interact with many people, other dogs, and animals and are the most commonly ... -
Effect of seasonal variation on milk sales and cattle vector-borne prevalence in Kiboga - Uganda
(Makerere University, 2022-08)The livestock sector in Uganda contributes 5% to the national GDP, 18.1% to agricultural GDP and 1- 1.5% to trade export value. However, livestock productivity is mainly affected by climate, disease vectors & diseases, and ... -
Identification of potential antigenic peptides of Bm86, Ra85A and Ra92A tick proteins using insilico tools and immune dot blot assay
(Makerere University, 2022-04-28)Ticks are the leading causes of losses the livestock sector in sub-Saharan Africa through the spread of tick-borne infections. They are mostly controlled by chemical acaricides. The use of anti-tick vaccine to control ticks ... -
Evaluation of a sample pooling strategy for SARS-COV-2 by real time PCR
(Makerere University, 2022)Coronavirus disease 2019 (COVID-19) started as a cluster of pneumonia cases in Wuhan, China in December 2019 and became a global pandemic of international concern. Timely laboratory diagnosis of COVID-19 of all samples ... -
Trypanosoma Brucei Brucei : host interactions associated with biological barrier traversal
(Makerere University, 2022)Trypanosoma brucei, the causative agents of African Trypanosomiasis cross different biological barriers resulting in serious disorders. This study investigated Trypanosome parasite host interactions associated with biological ... -
Assessment of poultry medication practices by farmers and veterinarians before specimen submission to Veterinary Diagnostic Laboratories in Makerere University
(Makerere University, 2022-03)In Uganda, the private sector is the major player in the distribution and use of veterinary drugs. This coupled with the laxity among drug regulatory bodies has enabled easy accessibility of veterinary drugs by farmers and ... -
Detection of carbapenem resistance due to outer membrane porin alteration in non carbapenemase producing E. coli and K. pneumoniae isolates from Mulago National Referral Hospital, Uganda
(Makerere University, 2022)Antimicrobial resistance is a global public health concern which compromises the use of antibiotics in the fight against microbes. Carbapenems are the most effective antibiotics for the treatment of clinical infections ... -
Effects of cytokine gene polymorphisms on il-10, tnf-α levels and oxidative stress in sickle cell disease patients from Mulago hospital, Uganda
(Makerere University, 2022-04-29)Sickle cell disease is a major cause of death in children under 5 years in Africa. Chronic oxidative stress and the release of inflammatory cytokines contribute to sickle cell disease pathogenesis and thus complicate the ... -
Ticks and tick-borne diseases of cattle in selected districts of Uganda : zoonotic potential and public health implications
(Makerere University, 2022)Background: According to the World Health Organization and other international health monitoring bodies, ticks have emerged as a major player in propagating human diseases, yet their involvement in zoonotic disease ... -
Rapid detection and antibiotic resistance of Group B Streptococcus from women at Kawempe Hospital Kampala, Uganda
(Makerere University, 2022)An accurate and rapid bedside test undertaken in labour ward to detect Group B Streptococcus (GBS) maternal colonization has the potential to improve the effectiveness of intrapartum antibiotic prophylaxis prevention ... -
Second-line drug resistance markers as indicators of time to sputum culture conversion among selected mycobacterium tuberculosis clinical isolates at the Uganda National Tuberculosis Reference Laboratory
(2022)Drug-resistant TB continues to be a global public health crisis, with low treatment success rates for Multi Drug Resistant/ Rifampicin Resistant TB and Extensively Drug-Resistant TB. Achieving sustained bacteriological ... -
Antimicrobial resistance of staphylococcus aureus; knowledge, attitude, and practices on antibiotic use among farmers in Isingiro and Kamuli districts – Uganda
(Makerere University, 2022)Bacterial resistance to antibiotics is fast becoming a big challenge as resistance to multiple drugs is rising rapidly. The emergence of resistant Staphylococcus aureus worldwide is life-threatening for both the human and ... -
Phytochemical composition of Capsicum frutescens and its effect on growth, carcass, organoleptic and feed cost parameters of indigenous and broiler chickens
(2022)Chicken meat is a major source of animal protein and its production has increased globally by 25% in the last decade mostly in Asia and Africa. However, due to the ever-increasing problem of antibiotic resistance, routine ... -
Seroprevalence and risk factors of Brucellosis in Camel and herdsmen in Benadir Region Somalia
(Makerere University, 2022)Camel brucellosis is a contagious disease that is often presented in a chronic condition caused by Brucella and affects both animals and pastoralists. The disease has been partially assessed in Somalia, especially since ...