College of Health Sciences (CHS): Recent submissions
Now showing items 221-240 of 3259
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Development of an Application Programming Interface for an Integrated Health Management Information System. A Case Study at CoRSU Hospital
(2024-09-13)Background Health facilities in Uganda have adopted health information systems most of which are disjointed and operate in silos within areas of limited resource settings. Inline to this is delayed provision of complete, ... -
Cerebrospinal fluid mononuclear cell profiling among patients with HIV associated cryptococcal meningitis: Immunological predictors of early mortality and 1 year survival
(Makerere University, 2024-09)Introduction: Despite the introduction of new treatment strategies for the induction phase of HIV-associated cryptococcal meningitis (CM), the 2-week mortality continues to be unacceptably high and at 1 year more than half ... -
Prevalence of systemic candidiasis, drug-resistant Candida species, and associated factors among febrile patients with cancer at Uganda Cancer Institute
(Makerere University, 2024)Background: A significant proportion of cancer-related deaths in sub-Saharan Africa are secondary to infections. Patients with cancer are at risk of fungal infections due to their lowered immunity and when these infections ... -
Development and evaluation of various SARS-CoV-2 detection tests in Nasopharyngeal specimens in Uganda
(Makerere University, 2024)Background: Although the WHO recommends RT-PCR as reference standard method for detection of SARS-CoV-2 nucleic acid when diagnosing COVID-19 and tracing of contacts, this test is costly, primarily designated for specialised ... -
Prevalence and Factors Associated with Hypovitaminosis D among Children on Treatment with Anti-Seizure Medications at Mulago Hospital
(Makerere University, 2024-09-16)Introduction: Epilepsy is the most common neurological disease in childhood that often requires long term treatment with anti-seizure medications. These drugs increase the metabolism of vitamin D posing a significant risk ... -
Prevalence and factors associated with Pulmonary Hypertension among adults living with HIV attending Kiruddu National Referral Hospital HIV-Clinic
(Makerere University, 2024-09-30)The introduction of effective combination antiretroviral therapy for HIV treatment has transformed HIV infection into a chronic infectious disease [1] as a result of decreased mortalities from AIDS and opportunistic ... -
The cascade of care and HIV clinical outcomes for diabetes mellitus among people with HIV at two large HIV Clinics in Kampala, Uganda: A sequential explanatory mixed methods study
(Makerere University, 2024-03)Background: The increased survival of people with HIV (PWH) in sub-Saharan Africa has led to a parallel rise in the prevalence of chronic non-communicable diseases (NCDs), particularly cardiovascular diseases and diabetes ... -
Determination of Anti-HBsAg antibody titers among children under five years who received Hepatitis B vaccine under UNEPI in Kawempe Division, Kampala-Uganda
(Makerere University, 2024)Background: Hepatitis B Virus is a global health threat with estimated 257 million people chronically infected with the infection (WHO 2017). HBsAg sero prevalence is approximately 3.6% with high endemicity observed in ... -
Factors associated with caregiver burden among adults caring for children admitted with severe acute malnutrition at Mulago Hospital, Kampala.
(Makerere University, 2024)Caregiving burden negatively influences caregivers' responses to their roles. It encompasses the distress and/or the extent of perceived adverse effects arising from fulfilling physical, emotional, financial, social, and ... -
Optimizing detection and early management of acute kidney injury using trained caregivers on the infectious disease wards of Kiruddu National Referral Hospital
(Makerere University, 2024-09-30)Background: Globally 13.3 million people develop AKI annually, with 85% in LMICs, largely due to infections and sepsis. AKI can be resolved in up to two-thirds of the patients with proper timely management. Current clinical ... -
Factors associated with length of hospital stay among sickle cell disease patients at Nalufenya and Mulago National Referral Hospitals: A cohort study.
(Makerere University, 2024)Introduction: Children with Sickle Cell Disease (SCD) suffer multiple and often prolonged hospitalizations. Increased length of hospital stay for these children has negative psychological, economic and health effects on ... -
Characterizing change in cough frequency and associated factors among patients with pulmonary tuberculosis using HYFE App in Kampala- Uganda
(Makerere University, 2024)Background: The most important means of pulmonary tuberculosis transmission is cough, which invariably results from an inflammatory reaction to pulmonary mycobacterial infection. A noticeable decrease in coughing is ... -
Knowledge attitudes and practices among healthcare workers on hepatitis B birth dose vaccination at Kawempe National Referral Hospital
(Makerere University, 2024)Introduction Hepatitis B virus (HBV) is a global public health challenge, with approximately 257 million people worldwide affected with chronic infections, with the highest in Asia and Sub-Saharan Africa. The majority ... -
Barriers and enablers of early health-seeking behaviour among women with preeclampsia and eclampsia at a National Referral Hospital
(Makerere University, 2024)Background Globally, about 2-8% of women experience hypertensive disorders in pregnancy (HDPs), including preeclampsia and eclampsia. These disorders are thus, the second leading cause of maternal mortality and morbidity ... -
Indication based typical diagnostic reference level for barium swallow examination at three centres in Kampala, Uganda
(Makerere University, 2024)Introduction: There is reduction in the utilization of barium examination which is attributable to concerns regarding the excessive exposure of ionizing radiations. Diagnostic Reference Levels (DRLs) are employed in ... -
Surgical site Infections and antimicrobial susceptibility patterns among patients undergoing abdominal surgery at Mulago National Referral Hospital: A prospective cohort study
(Makerere University, 2024)Background: Surgical site infections (SSIs) remain a major cause of morbidity and mortality among post-operative patients. The care for these patients is further compromised by the ever-increasing antimicrobial resistance. ... -
Prevalence, practices and challenges of home management of pain among children with sickle cell anaemia attending Mulago Sickle Cell Clinic
(Makerere University, 2024)BACKGROUND The most problematic aspect of managing sickle cell disease is the pain caused by vaso-occlusion . Despite a good follow-up of the patients, the vaso-occlusive crises remain unpredictable and have an uncertain ... -
Diagnostic accuracy of anomaly screening ultrasound scan in sex identification of the fetus, at two selected centers in Kampala, Uganda
(Makerere University, 2024)Background: The role of ultrasound scan in obstetric is unquestionably paramount. Over the years the use of ultrasound has evolved to a more sophisticated role such as sex identification. Sex identification remains a ... -
Prevalence and factors associated with missed opportunities for tuberculosis diagnosis among children under 15 years attending Kitgum General Hospital Outpatient Department
(Makerere University, 2024)Background: Childhood TB remains a leading cause of death globally. In 2020, 1.1 million children fell ill with TB, but only 36.5% were reported to the WHO. An estimated 3 million TB cases are missed annually by healthcare ... -
Cerebral dominace and side of stroke among patients attending Neuro-Clinics in Uganda: A cross sectional study of Mulago and Kirudu National Referral Hospitals
(Makerere University, 2024)Introduction: Non-dominant hemispheric strokes have been associated with more severe stroke, longer recovery time and much slower return of functional activity compared to the dominant side. During activity Functional MRI ...