College of Health Sciences (CHS): Recent submissions
Now showing items 201-220 of 3353
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Evaluation of the Liofilchem rapid ESBL NP test for the detection of extended spectrum beta-lactamases in Enterobacteriacea in complicated urinary tract infections at Mulago Hospital using direct urine samples
(Makerere University, 2024)Introduction: There is a growing burden of UTIs complicated by drug resistant microorganisms. Antimicrobial resistance (AMR) is a growing global public health threat, with extended- spectrum beta-lactamase (ESBL) producing ... -
Application of mathematical modelling to determine the most optimal combinational strategy for controlling the spread of HIV/AIDS among sexually active adults in fishing communities around Lake Victoria in Uganda
(Makerere University, 2024)With an estimated 1.5 million new infections in 2021, HIV remains a major global health problem. In countries such as Uganda with mature generalized epidemics, there are still groups of individuals that are disproportionately ... -
Prevalence of false negative HIV results and associated factors among patients on antiretroviral therapy with a non-detectable viral load at Kisenyi Health Center IV
(Makerere University, 2024)Introduction: Studies in Sub Saharan Africa have found decreasing sensitivities of HIV diagnostic tests among people living with HIV (PLHIV) that have an undetectable viral load. This has often led to inappropriate ... -
Prevalence and factors associated with low-level viremia among PLHIV substituted to Dolutegravir from non-nucleotide reverse transcriptase inhibitors at Kitebi Health Center III
(Makerere University, 2024)Introduction: Globally, 38.4 million people were living with HIV by the end of 2021, and about two-thirds of this population were in the sub-Saharan region. Effective adherence to combination antiretroviral therapy (ART) ... -
Concordance of data on key malaria indicators between DHIS 2 and source documents and its influencing factors at health facilities in Mayuge District, Uganda
(Makerere University, 2024)Introduction: Effective malaria surveillance is a key strategy for malaria control in sub-Saharan Africa. Uganda rolled out the District Health Information System, version 2 (DHIS 2) to improve routine malaria surveillance ... -
Model-based prediction of Dolutegravir dose requirement for HIV exposed neonates in Uganda
(Makerere University, 2024)Introduction: Mother-to-child transmission of HIV is the primary source of HIV infections in children, especially in low-income countries accounting for 14% of all new infections in Uganda. It is recommended that HIV-exposed ... -
Outcomes of birth asphyxia and associated factors among newborns
(Makerere University, 2024)Birth asphyxia is a serious clinical problem that is associated with life-threatening complication like Hypoxic Ischemic Encephalopathy (HIE). Hypoxic Ischemic Encephalopathy carries high case fatality rates ranging between ... -
Microbial environmental contamination and infection prevention and control practices in the maternity ward of Buwenge General Hospital
(Makerere University, 2024)A 2017 review found that 42.6% of African countries lacked adequate antimicrobial resistance data, with widespread resistance among clinical isolates. In Uganda, despite IPC guidelines, healthcare workers often lack ... -
Prevalence and factors associated with generalized anxiety disorder in healthcare workers at China-Uganda Friendship Hospital Naguru and Kiruddu National Referral Hospital
(Makerere University, 2024)Background: Generalized anxiety disorder is common in health workers and is associated with reduced productivity at the work place as the patients are usually restless and, on the edge, irritable with difficulty in ... -
Knowledge, attitude and practices (KAP) among clinicians on aetiologic management of abnormal vaginal discharge in pregnant women at Kawempe National Referral Hospital.
(Makerere University, 2024-07)Introduction: Aetiologic management of STIs to treat the curable abnormal vaginal discharge caused by bacterial vaginosis, chlamydia, gonorrhea, and trichomoniasis is a sensitive and specific tool to achieve WHO’s global ... -
Prevalence and factors associated with premarital sickle cell screening among couples at the different religious institutions in Kampala District: a cross-sectional study.
(Makerere University, 2024-10)Introduction: Premarital screening provides an opportunity for intending couples to know their phenotype or genotype and be aware of the risk of having children with genetic diseases like sickle cell disease (SCD) and adopt ... -
Knowledge, attitude and practices of preconception care amongst healthcare providers at kawempe national referral hospital
(Makerere University, 2024-12-09)Introduction: Preconception care aims to enhance a healthy physical, mental, and emotional well-being of a woman or couple before conception and has been endorsed by WHO to improve maternal outcomes. Despite acknowledged ... -
Prevalence and factors associated with failed induction of labor in Kawempe National Referral Hospital
(Makerere University, 2024-12-06)Background: Induction of labor is the artificial stimulation of uterine contractions before the spontaneous onset of labor to achieve vaginal delivery. Failed induction of labor is associated with poor maternal and neonatal ... -
Prevalence of pneumonia and associated risk factors among neonates in selected Health Centre IVs in Wakiso district from February 2024 to June 2024
(Makerere University, 2024)Background: Pneumonia remains a significant problem especially among neonates in health centre IVs which barely have NICUs in place. Whereas the MOH has implemented the Integrated Community Case Management on three killer ... -
Prevalence and factors associated with acute kidney injury among women with preeclmapsia with severe features in Kawempe National Referral Hospital
(Makerere University, 2024-12-11)Background: Preeclampsia is one of the most common cause of pregnancy related Acute Kidney Injury (AKI) accounting for up to 30% of global cases. However, there is limited research conducted in Uganda on prevalence and ... -
Assessing the implementation fidelity of self-collect HPV cervical cancer screening among HIV positive women in Wakiso District, Uganda; a survey of public healthcare facilities.
(Makerere University, 2024-12-06)Cervical cancer is the fourth most common cancer affecting women worldwide with an estimated 640,000 new cases in 2020 and an estimated 342,000 deaths. In Uganda, cervical cancer remains the most common cause of cancer ... -
Prevalence of and factors associated with cervical precancerous lesions among women aged 25-65 years attending Uganda Cancer Institute comprehensive cancer community programs
(Makerere University, 2024-10)Cervical cancer is a significant global issue, with 604,000 new cases in 2022. Women with HIV face a sixfold higher risk. In Uganda, despite efforts like HPV vaccination and cervical cancer screening, around 7,000 cases ... -
Evaluation of anticonvulsant activity of the aqueous and total crude extracts of Vernonia amygdalina Delile in pentylenetetrazole-induced seizures in wistar albino rats
(Makerere University, 2024-11-07)Introduction: Seizures due to abnormal electrical activity in the brain leading to convulsions and hence epilepsy have continued to be a serious problem among the population globally including in Uganda. Medicinal plants ... -
Risk of respiratory distress syndrome in preterm neonates born to mothers who receivec antenatal dexamethasone between 2 weeks 0 days and 33 weeks days at kawempe national referral hospital
(Makerere University, 2024-12-06)Introduction: Respiratory distress syndrome (RDS) is a serious complication of preterm birth and is the main cause of perinatal mortality. Corticosteroids have reported to have a positive effect on the mother and fetus ... -
Factors associated with uptake of community-led total sanitation practices and behavior among triggered and followed-up households and communities in Agorigiroi Sub County, Rural Ngora District
(Makerere University, 2024)Background: Community Led Total Sanitation (CLTS) practices and behaviors have been emphasized and promoted during community wide mobilizations to improve sanitation, enforced through non-coercive efforts for households ...