College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3259
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Treatment outcomes of isoniazid mono-resistant mycobacterium tuberculosis patients in Uganda: a retrospective cross-sectional study from 2017 to 2022
(Makerere University, 2024-10)Globally, isoniazid-resistant, rifampicin-susceptible TB is estimated to occur in 13.1% (95% confidence interval [CI]: 9.9–16.9%) of new cases and 17.4% (95% CI: 0.5–54.0%) of previously treated cases. Current WHO guidelines ... -
Occurrence of quinolone resistance genes qep, QnrA, QnrB and QnrS in uropathogenic E. coli from female clinical samples at Makerere University College of Health Sciences
(Makerere University, 2022)Drug resistant Escherichia coli (E Coli) is the leading cause of community and hospital acquired urinary tract infections affecting approximate 150 million people each year worldwide. Uropathogenic Escherichia coli (UPEC) ... -
Prevalence and factors associated with nasal fractures among patients with head trauma at Mulago National Referral Hospital
(Makerere University, 2024)Introduction: Nasal fractures are the most common type of facial fractures contributing 40 - 58% of all facial fractures. Although very common, their assessment and management is rarely included in the routine care of ... -
Prevalence and factors associated with renal disease among HIV infected children on antiretroviral therapy attending Joint Clinical Research Center, Lubowa, Kampala
(Makerere University, 2021)Introduction: About 1.8 million children under the age of 15 years are living with HIV globally, 90% of these are in sub-Saharan Africa. In Uganda, 90,000 children between 0 and 14 years are estimated to be living with ... -
Levels of heavy metal concentration in leachate, borehole, and spring water in areas surrounding Kiteezi Landfill, Wakiso District, Uganda
(Makerere University, 2024)Rapid urbanization in developing countries has led to challenges in municipal solid waste management, including inadequate disposal in overflowing landfills lacking modern containment infrastructure. This results in ... -
The informed consent process for emergency surgery at public and private hospital surgical emergency units in the urban Ugandan setting
(Makerere University, 2024)Introduction: Informed consent is a process that can have challenges when required for emergency surgery, because the patient might not have the capacity to consent, and consent may be obtained from the next of kin, or ... -
Prevalence and factors associated with use of unrecommendable cord care substances among women 15-49 years in Uganda; a retrospective cross-sectional study
(Makerere University, 2024)In 2021, globally, 2.3 million neonates aged 0-28 days died, amounting to approximately 6,400 deaths per day, with Uganda accounting for 81 daily deaths. Sepsis, partly caused by poor cord care, is responsible for 18.2% ... -
Substance use among boda boda riders (commercial motorcyclists) working in Kamwokya Slum, Kampala Capital City, Uganda
(Makerere University, 2024)In Uganda, commercial motorcyclists (Boda boda riders) in slums are vulnerable road users whose road use is significantly impaired by substance use. Therefore, the study was carried out to to assess the determinants of ... -
Accuracy of the M-kit absolute concentration method for detection of drug-resistant mycobacterium tuberculosis in Uganda
(Makerere University, 2024)With an increasing incidence of multidrug-resistant tuberculosis (MDR-TB), accurate drug susceptibility testing (DST) of Mycobacterium tuberculosis to first-line and second-line plus new individualized anti-TB drugs has ... -
Prevalence of pregnancy risk behaviour and associated factors among sexually active adolescent girls aged 10-17 years in Uganda: secondary analysis of the adolescent girls and young women 2018 survey data
(Makerere University, 2024)In the last decade, a slow decline in teenage pregnancy was registered, often stalling within sub-Saharan African countries. However, recent evidence indicates an increasing trend in teenage pregnancies, common among girls ... -
CD133 protein expression in primary liver cancer; associated demographic and histopathological characteristics in Uganda
(Makerere University, 2024)Primary liver cancer is a leading cause of cancer morbidity and mortality. Globally, it is the 6th most common cancer and the 3rd most common cause of cancer deaths. In Uganda, liver cancer is the 7th most common cancer ... -
Factors associated with COVID-19 vaccine uptake in the slums of Kawempe Division, Kampala District
(Makerere University, 2024)Although the World Health Organization recommended vaccination as the most effective way to prevent novel coronavirus disease (COVID-19), uptake of COVID-19 vaccines remains suboptimal in low-income countries such as Uganda. ... -
A semantic interoperability framework for contextualising common standards supporting health information exchange in Uganda's healthcare ecosystem
(Makerere University, 2024)Introduction: Uganda’s healthcare system faces challenges of fragmented data systems, inadequate infrastructure, and limited resources, hindering effective information exchange and care coordination. More than 50 digital ... -
A genome-wide association study of blood urea nitrogen levels in the Uganda Genome Resource Cohort
(Makerere University, 2024)Blood urea nitrogen (BUN) is a key biomarker of kidney function, reflecting the balance between urea production and excretion. Elevated BUN levels are associated with impaired kidney function and serve as a diagnostic and ... -
Factors associated with hospital-acquired diarrhea among children (0-59 months) with severe acute malnutrition at Mwanamugimu Nutrition Unit, Mulago National Referral Hospital, Kampala District
(Makerere University, 2024)Introduction: Hospital-acquired diarrhea remains a major global public health concern and is one of the leading causes of morbidity and mortality among children with severe acute malnutrition. In Uganda, Hospital acquired ... -
Understanding the facilitators and barriers to dog mass vaccination campaigns in Uganda, A case of Kyegegwa District
(Makerere University, 2024)Background: Despite the annual commitment to procure 500,000 rabies vaccine doses and distributing them to districts freely on request, Uganda still grapples with a low dog vaccination coverage of about 10%. This study ... -
Assessing comprehension of informed consent among research participants enrolled in a malaria prevention study at Masafu Hospital, Busia District
(Makerere University, 2024)Introduction: Comprehension of informed consent by research participants is a fundamental pillar of the informed consent process. Participants quite often have low comprehension of medical procedures, risks and complications. ... -
Newborn care practices in Nakapiripirit District, North Eastern Uganda: A community-based cross-sectional study
(Makerere University, 2024)Introduction: Despite improved health facility deliveries in Uganda, the neonatal mortality rate has only improved marginally over the last three decades. Karamoja region in North-Eastern Uganda has one of the poorest ... -
Isoniazid hair drug levels among drug-susceptible pulmonary tuberculosis patients: A study to monitor exposure, adherence and treatment outcomes
(Makerere University, 2024)Background: Tuberculosis (TB) is still a major public health problem globally and in Uganda.Therapeutic drug monitoring (TDM) for TB improves treatment outcomes and mitigates the emergence of drug resistance (DR). Despite ... -
Enablers and barriers to adoption of the recommended infant feeding practices among primary caregivers with infants and young children in BidiBidi Refugee Settlement, Yumbe District
(Makerere University, 2024)Introduction Infant and Young Child Feeding (IYCF) practices are vital for reducing childhood morbidity and mortality. Globally, only about 42 percent of women begin breastfeeding within the first one hour of birth, 41% ...