Malaria remains a major public health concern especially among pregnant women and young children in sub-Saharan Africa. Few studies in Uganda have examined congenital malaria (CM) defined as presence of malaria parasites ...

Plasmodium falciparum resistance mutations to aminoquinoline antimalarials are selected by prior drug use and may alter parasite fitness yet their associations with clinical malaria presentations are uncertain. ...

Ferritin, a highly conserved iron storage protein that sequesters iron from pathogens including Plasmodium falciparum, is part of the acute phase response in malaria pathogenesis. Ferritin levels are elevated in severe ...

This thesis focused on malaria vaccinology and employed reverse vaccinology and molecular techniques to predict potential vaccine candidates against P. falciparum malaria. Reverse vaccinology is fundamentally an in silico ...

Intermittent preventive treatment in pregnancy (IPTp) with monthly sulfadoxine-pyrimethamine (SP) is recommended for malaria-endemic parts of Africa, but efficacy is compromised by resistance and, in recent trials, ...